ENSG00000132698


Homo sapiens

Features
Gene ID: ENSG00000132698
  
Biological name :RAB25
  
Synonyms : P57735 / RAB25 / RAB25, member RAS oncogene family
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: q22
Gene start: 156061160
Gene end: 156070514
  
Corresponding Affymetrix probe sets: 218186_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000354376
NCBI entrez gene - 57111     See in Manteia.
OMIM - 612942
RefSeq - NM_020387
RefSeq Peptide - NP_065120
swissprot - P57735
Ensembl - ENSG00000132698
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rab25aENSDARG00000058800Danio rerio
 rab25bENSDARG00000052954Danio rerio
 ENSGALG00000029812Gallus gallus
 Rab25ENSMUSG00000008601Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P62491 / RAB11A / RAB11A, member RAS oncogene familyENSG0000010376961
Q15907 / RAB11B / RAB11B, member RAS oncogene familyENSG0000018523660
RAB4B / P61018 / RAB4B, member RAS oncogene familyENSG0000016757843
RAB4B-EGLN2 / RAB4B-EGLN2 readthrough (NMD candidate)ENSG0000017157043
RAB2A / P61019 / RAB2A, member RAS oncogene familyENSG0000010438841
RAB14 / P61106 / RAB14, member RAS oncogene familyENSG0000011939641
RAB4A / P20338 / RAB4A, member RAS oncogene familyENSG0000016811841
RAB2B / Q8WUD1 / RAB2B, member RAS oncogene familyENSG0000012947240
RAB18 / Q9NP72 / RAB18, member RAS oncogene familyENSG0000009924637
Q96DA2 / RAB39B / RAB39B, member RAS oncogene familyENSG0000015596137
Q14964 / RAB39A / RAB39A, member RAS oncogene familyENSG0000017933136
RAB42 / Q8N4Z0 / RAB42, member RAS oncogene familyENSG0000018806013


Protein motifs (from Interpro)
Interpro ID Name
 IPR001806  Small GTPase superfamily
 IPR005225  Small GTP-binding protein domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003382 epithelial cell morphogenesis IEA
 biological_processGO:0008284 positive regulation of cell proliferation IDA
 biological_processGO:0010634 positive regulation of epithelial cell migration IMP
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0031268 pseudopodium organization IDA
 biological_processGO:0060627 regulation of vesicle-mediated transport IMP
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031143 pseudopodium IDA
 cellular_componentGO:0031260 pseudopodium membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005525 GTP binding IEA
 molecular_functionGO:0031489 myosin V binding IPI


Pathways (from Reactome)
Pathway description
RAB geranylgeranylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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