ENSG00000132911


Homo sapiens

Features
Gene ID: ENSG00000132911
  
Biological name :NMUR2
  
Synonyms : neuromedin U receptor 2 / NMUR2 / Q9GZQ4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: -1
Band: q33.1
Gene start: 152391532
Gene end: 152433368
  
Corresponding Affymetrix probe sets: 224088_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000255262
NCBI entrez gene - 56923     See in Manteia.
OMIM - 605108
RefSeq - NM_020167
RefSeq - XM_011537670
RefSeq Peptide - NP_064552
swissprot - Q9GZQ4
Ensembl - ENSG00000132911
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 NMUR2ENSGALG00000004101Gallus gallus
 Nmur2ENSMUSG00000037393Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NMUR1 / Q9HB89 / neuromedin U receptor 1ENSG0000017159644
MLNR / O43193 / motilin receptorENSG0000010253927
NTSR1 / P30989 / neurotensin receptor 1ENSG0000010118825
GHSR / Q92847 / growth hormone secretagogue receptorENSG0000012185324
TRHR / P34981 / thyrotropin releasing hormone receptorENSG0000017441724
GPR39 / O43194 / G protein-coupled receptor 39ENSG0000018384024
NTSR2 / O95665 / neurotensin receptor 2ENSG0000016900623


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR005390  Neuromedin U receptor
 IPR005392  Neuromedin U receptor, type 2
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002023 reduction of food intake in response to dietary excess IEA
 biological_processGO:0006816 calcium ion transport IDA
 biological_processGO:0006940 regulation of smooth muscle contraction NAS
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway IDA
 biological_processGO:0007204 positive regulation of cytosolic calcium ion concentration IDA
 biological_processGO:0007218 neuropeptide signaling pathway IEA
 biological_processGO:0007267 cell-cell signaling TAS
 biological_processGO:0007417 central nervous system development IEP
 biological_processGO:0007625 grooming behavior IEA
 biological_processGO:0007631 feeding behavior TAS
 biological_processGO:0019722 calcium-mediated signaling NAS
 biological_processGO:0034220 ion transmembrane transport IEA
 biological_processGO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling IDA
 biological_processGO:0048016 inositol phosphate-mediated signaling IDA
 biological_processGO:0048265 response to pain IEA
 biological_processGO:0050482 arachidonic acid secretion IDA
 biological_processGO:0051930 regulation of sensory perception of pain IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IDA
 molecular_functionGO:0001607 neuromedin U receptor activity IDA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity TAS
 molecular_functionGO:0005229 intracellular calcium activated chloride channel activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005525 GTP binding IDA
 molecular_functionGO:0008188 neuropeptide receptor activity IEA
 molecular_functionGO:0042924 neuromedin U binding IDA


Pathways (from Reactome)
Pathway description
Peptide ligand-binding receptors
G alpha (q) signalling events
G alpha (i) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000109255 NMU / P48645 / neuromedin U  / complex / reaction
 ENSG00000204640 NMS / Q5H8A3 / neuromedin S  / complex / reaction






 

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