ENSG00000171596


Homo sapiens

Features
Gene ID: ENSG00000171596
  
Biological name :NMUR1
  
Synonyms : neuromedin U receptor 1 / NMUR1 / Q9HB89
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: -1
Band: q37.1
Gene start: 231523160
Gene end: 231530495
  
Corresponding Affymetrix probe sets: 221383_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000305877
NCBI entrez gene - 10316     See in Manteia.
OMIM - 604153
RefSeq - NM_006056
RefSeq - XM_011510487
RefSeq Peptide - NP_006047
swissprot - Q9HB89
Ensembl - ENSG00000171596
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nmur1aENSDARG00000060884Danio rerio
 nmur1bENSDARG00000003944Danio rerio
 NMUR1ENSGALG00000007714Gallus gallus
 Nmur1ENSMUSG00000026237Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NMUR2 / Q9GZQ4 / neuromedin U receptor 2ENSG0000013291142
MLNR / O43193 / motilin receptorENSG0000010253928
GHSR / Q92847 / growth hormone secretagogue receptorENSG0000012185327
NTSR1 / P30989 / neurotensin receptor 1ENSG0000010118826
NTSR2 / O95665 / neurotensin receptor 2ENSG0000016900626
TRHR / P34981 / thyrotropin releasing hormone receptorENSG0000017441722
GPR39 / O43194 / G protein-coupled receptor 39ENSG0000018384021


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR005390  Neuromedin U receptor
 IPR005391  Neuromedin U receptor, type 1
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006816 calcium ion transport IDA
 biological_processGO:0006821 chloride transport IDA
 biological_processGO:0006939 smooth muscle contraction IEP
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway IDA
 biological_processGO:0007202 activation of phospholipase C activity IDA
 biological_processGO:0007218 neuropeptide signaling pathway IEA
 biological_processGO:0019722 calcium-mediated signaling IDA
 biological_processGO:0048016 inositol phosphate-mediated signaling IDA
 biological_processGO:1903955 positive regulation of protein targeting to mitochondrion IMP
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IDA
 molecular_functionGO:0001607 neuromedin U receptor activity IDA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity TAS
 molecular_functionGO:0008188 neuropeptide receptor activity IEA
 molecular_functionGO:0042924 neuromedin U binding IDA


Pathways (from Reactome)
Pathway description
Peptide ligand-binding receptors
G alpha (q) signalling events
G alpha (i) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000109255 NMU / P48645 / neuromedin U  / complex / reaction






 

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