ENSG00000135480


Homo sapiens
filamentKRT7intermediateproteinkeratintypeiikeratinizationconservedsiteheadviralprocesscornificationnucleuscytoplasmcytosolextracellularexosomestructuralmoleculeactivitybindingformationcornifiedenvelope

Features
Gene ID: ENSG00000135480
  
Biological name :KRT7
  
Synonyms : keratin 7 / KRT7 / P08729
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: 1
Band: q13.13
Gene start: 52232520
Gene end: 52252186
  
Corresponding Affymetrix probe sets: 209016_s_at (Human Genome U133 Plus 2.0 Array)   214031_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000492421
Ensembl peptide - ENSP00000329243
NCBI entrez gene - 3855     See in Manteia.
OMIM - 148059
RefSeq - XM_017019294
RefSeq - NM_005556
RefSeq - XM_011538325
RefSeq Peptide - NP_005547
swissprot - P08729
swissprot - A0A1W2PRP1
Ensembl - ENSG00000135480
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 krt4ENSDARG00000017624Danio rerio
 krt5ENSDARG00000058371Danio rerio
 krt8ENSDARG00000058358Danio rerio
 zgc:158846ENSDARG00000058462Danio rerio
 KRT7ENSGALG00000034868Gallus gallus
 Krt7ENSMUSG00000023039Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
KRT5 / P13647 / keratin 5ENSG0000018608165
KRT6A / P02538 / keratin 6AENSG0000020542065
KRT75 / O95678 / keratin 75ENSG0000017045464
KRT6C / P48668 / keratin 6CENSG0000017046564
KRT6B / P04259 / keratin 6BENSG0000018547964
KRT3 / P12035 / keratin 3ENSG0000018644261
KRT8 / P05787 / keratin 8ENSG0000017042160
KRT76 / Q01546 / keratin 76ENSG0000018506959
KRT79 / Q5XKE5 / keratin 79ENSG0000018564059
KRT4 / P19013 / keratin 4ENSG0000017047757
KRT71 / Q3SY84 / keratin 71ENSG0000013964856
KRT1 / P04264 / keratin 1ENSG0000016776855


Protein motifs (from Interpro)
Interpro ID Name
 IPR001664  Intermediate filament protein
 IPR003054  Keratin, type II
 IPR018039  Intermediate filament protein, conserved site
 IPR032444  Keratin type II head


Gene Ontology (GO)
interspecies interaction between organismsanatomical structure developmentcellular developmental processcell deathinterspecies interaction between organismsanatomical structure developmentcellular developmental processcell deathinterspecies interaction between organismsanatomical structure developmentcellular developmental processcell deathinterspecies interaction between organismsanatomical structure developmentcellular developmental processcell deathinterspecies interaction between organismsanatomical structure developmentcellular developmental processcell deathinterspecies interaction between organismsanatomical structure developmentcellular developmental processcell deathinterspecies interaction between organismsanatomical structure developmentcellular developmental processcell deathinterspecies interaction between organismsanatomical structure developmentcellular developmental processcell deathinterspecies interaction between organismsanatomical structure developmentcellular developmental processcell deathinterspecies interaction between organismsanatomical structure developmentcellular developmental processcell deathinterspecies interaction between orinterspecies interaction between organismsanatomical structure developmentanatomical structure developmentcellular developmental processcellular developmental processcell deathcell death
protein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein binding
cellorganellesupramolecular complexextracellular regioncellorganellesupramolecular complexextracellular regioncellorganellesupramolecular complexextracellular regioncellorganellesupramolecular complexextracellular regioncellorganellesupramolecular complexextracellular regioncellorganellesupramolecular complexextracellular regioncellorganellesupramolecular complexextracellular regioncellorganellesupramolecular complexextracellular regioncellorganellesupramolecular complexextracellular regioncellorganellesupramolecular complexextracellular regioncellcellorganelleorganellesupramolecular complexsupramolecular complexextracellular regionextracellular region
TypeGO IDTermEv.Code
 biological_processGO:0016032 viral process IEA
 biological_processGO:0031424 keratinization TAS
 biological_processGO:0070268 cornification TAS
 cellular_componentGO:0005634 nucleus HDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005882 intermediate filament IEA
 cellular_componentGO:0045095 keratin filament IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005198 structural molecule activity IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Keratinization
Formation of the cornified envelope


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr