ENSMUSG00000023039


Mus musculus

Features
Gene ID: ENSMUSG00000023039
  
Biological name :Krt7
  
Synonyms : Keratin, type II cytoskeletal 7 / Krt7 / Q9DCV7
  
Possible biological names infered from orthology : keratin 7 / P08729
  
Species: Mus musculus
  
Chr. number: 15
Strand: 1
Band: F2
Gene start: 101411043
Gene end: 101430313
  
Corresponding Affymetrix probe sets: 10427052 (MoGene1.0st)   1423952_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000117046
Ensembl peptide - ENSMUSP00000069900
NCBI entrez gene - 110310     See in Manteia.
MGI - MGI:96704
RefSeq - NM_033073
RefSeq Peptide - NP_149064
swissprot - D3Z6N5
swissprot - Q9DCV7
Ensembl - ENSMUSG00000023039
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 krt4ENSDARG00000017624Danio rerio
 krt5ENSDARG00000058371Danio rerio
 krt8ENSDARG00000058358Danio rerio
 zgc:158846ENSDARG00000058462Danio rerio
 KRT7ENSGALG00000034868Gallus gallus
 KRT7ENSG00000135480Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Krt6a / P50446 / Keratin, type II cytoskeletal 6A / KRT6B* / KRT6C* / P04259* / P48668* / P02538* / keratin 6A* / keratin 6B* / keratin 6C*ENSMUSG0000005835464
Krt6b / keratin 6B / KRT6A* / KRT6C* / P02538* / P04259* / P48668* / keratin 6A* / keratin 6C*ENSMUSG0000002304163
Krt5 / Q922U2 / keratin 5 / P13647*ENSMUSG0000006152763
Krt75 / Q8BGZ7 / Keratin, type II cytoskeletal 75 / O95678* / keratin 75*ENSMUSG0000002298662
Krt90ENSMUSG0000004869962
Krt8 / P11679 / Keratin, type II cytoskeletal 8 / P05787* / keratin 8*ENSMUSG0000004938259
Krt76 / Q3UV17 / Keratin, type II cytoskeletal 2 oral / Q01546* / keratin 76*ENSMUSG0000007540259
Krt4 / P07744 / Keratin, type II cytoskeletal 4 / P19013* / keratin 4*ENSMUSG0000005966858
Krt79 / Q8VED5 / Keratin, type II cytoskeletal 79 / Q5XKE5* / keratin 79*ENSMUSG0000006139758
Gm5414 / KRT6A* / KRT6B* / KRT6C* / P04259* / P48668* / P02538* / keratin 6A* / keratin 6B* / keratin 6C*ENSMUSG0000006423256
Gm5478 / KRT6A* / KRT6B* / KRT6C* / P04259* / P48668* / P02538* / keratin 6A* / keratin 6B* / keratin 6C*ENSMUSG0000009524156


Protein motifs (from Interpro)
Interpro ID Name
 IPR001664  Intermediate filament protein
 IPR003054  Keratin, type II
 IPR018039  Intermediate filament protein, conserved site
 IPR032444  Keratin type II head


Gene Ontology (GO)
TypeGO IDTermEv.Code
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005882 intermediate filament IEA
 cellular_componentGO:0045095 keratin filament IEA
 molecular_functionGO:0005198 structural molecule activity IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Keratinization
Formation of the cornified envelope


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000195 hypocalcemia "subnormal concentrations of calcium ions in the circulating blood " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Kdm8tm1b(EUCOMM)Wtsi/Kdm8tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Kdm8tm1b(EUCOMM)Wtsi/Ics

 MP:0000351 increased cell proliferation "greater than the normal growth and reproduction of similar cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Dscam3J/Dscam3J
Genetic Background: involves: C3H/HeSnSmn * CB17

 MP:0002702 decreased circulating free fatty acid level "lower than normal levels of unesterified fatty acids in the blood" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Kdm8tm1b(EUCOMM)Wtsi/Kdm8tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Kdm8tm1b(EUCOMM)Wtsi/Ics

 MP:0010386 abnormal urinary bladder physiology "any functional anomaly of the distensible musculomembranous organ that serves to collect and store urine excreted by the kidneys" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Dscam3J/Dscam3J
Genetic Background: involves: C3H/HeSnSmn * CB17

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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