ENSG00000140044


Homo sapiens
JDP2bindingregulationrnapolymeraseiidnafactoractivityproteinsequence-specificdomaindna-bindingdna-templatedhistonedeacetylationproximalpromoterap-basic-leucinezipperskn--likesuperfamilyjundimerizationfatcelldifferentiationnucleus

Features
Gene ID: ENSG00000140044
  
Biological name :JDP2
  
Synonyms : JDP2 / Jun dimerization protein 2 / Q8WYK2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 14
Strand: 1
Band: q24.3
Gene start: 75427716
Gene end: 75474111
  
Corresponding Affymetrix probe sets: 226267_at (Human Genome U133 Plus 2.0 Array)   239085_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000267569
Ensembl peptide - ENSP00000409787
Ensembl peptide - ENSP00000415558
Ensembl peptide - ENSP00000452769
Ensembl peptide - ENSP00000399587
NCBI entrez gene - 122953     See in Manteia.
OMIM - 608657
RefSeq - XM_017020975
RefSeq - NM_001135049
RefSeq - NM_130469
RefSeq - XM_005267332
RefSeq - XM_017020971
RefSeq - XM_017020972
RefSeq - XM_017020973
RefSeq - XM_017020974
RefSeq - NM_001135047
RefSeq - NM_001135048
RefSeq Peptide - NP_569736
RefSeq Peptide - NP_001128519
RefSeq Peptide - NP_001128520
RefSeq Peptide - NP_001128521
swissprot - Q8WYK2
swissprot - H0YKE4
swissprot - A0A024R6D7
Ensembl - ENSG00000140044
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 jdp2aENSDARG00000040137Danio rerio
 JDP2ENSGALG00000010322Gallus gallus
 Jdp2ENSMUSG00000034271Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ATF3 / P18847 / activating transcription factor 3ENSG0000016277247


Protein motifs (from Interpro)
Interpro ID Name
 IPR000837  AP-1 transcription factor
 IPR004827  Basic-leucine zipper domain
 IPR008917  Transcription factor, Skn-1-like, DNA-binding domain superfamily
 IPR029819  Jun dimerization protein 2


Gene Ontology (GO)
nitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcellular component organizationcellular developmental processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcellular component organizationcellular developmental processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcellular component organizationcellular developmental processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcellular component organizationcellular developmental processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcellular component organizationcellular developmental processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcellular component organizationcellular developmental processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcellular component organizationcellular developmental processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcellular component organizationcellular developmental processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcellular component organizationcellular developmental processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcellular component organizationcellular developmental processnitrogen compound menitrogen compound metabolic processbiosynthetic processbiosynthetic processcellular metabolic pcellular metabolic processprimary metabolic prprimary metabolic processorganic substance meorganic substance metabolic processcellular component ocellular component organizationcellular developmentcellular developmental process
organic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitychromatin bindingprotein bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitychromatin bindingprotein bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitychromatin bindingprotein bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitychromatin bindingprotein bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitychromatin bindingprotein bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitychromatin bindingprotein bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitychromatin bindingprotein bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitychromatin bindingprotein bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitychromatin bindingprotein bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitychromatin bindingprotein bindingorganic cyclic compound bindorganic cyclic compound bindingheterocyclic compound bindinheterocyclic compound bindingDNA-binding transcription faDNA-binding transcription factor activitychromatin bindingchromatin bindingprotein bindingprotein binding
cellorganellecellorganellecellorganellecellorganellecellorganellecellorganellecellorganellecellorganellecellorganellecellorganellecellcellorganelleorganelle
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0031063 regulation of histone deacetylation IEA
 biological_processGO:0031065 positive regulation of histone deacetylation IEA
 biological_processGO:0045599 negative regulation of fat cell differentiation IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding ISM
 molecular_functionGO:0001078 transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003682 chromatin binding IEA
 molecular_functionGO:0003690 double-stranded DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0046982 protein heterodimerization activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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