ENSG00000141429


Homo sapiens

Features
Gene ID: ENSG00000141429
  
Biological name :GALNT1
  
Synonyms : GALNT1 / polypeptide N-acetylgalactosaminyltransferase 1 / Q10472
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 18
Strand: 1
Band: q12.2
Gene start: 35581117
Gene end: 35711834
  
Corresponding Affymetrix probe sets: 1568618_a_at (Human Genome U133 Plus 2.0 Array)   201722_s_at (Human Genome U133 Plus 2.0 Array)   201723_s_at (Human Genome U133 Plus 2.0 Array)   201724_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000465452
Ensembl peptide - ENSP00000466411
Ensembl peptide - ENSP00000465699
Ensembl peptide - ENSP00000269195
Ensembl peptide - ENSP00000465341
NCBI entrez gene - 2589     See in Manteia.
OMIM - 602273
RefSeq - XM_017025692
RefSeq - NM_020474
RefSeq - XM_005258239
RefSeq Peptide - NP_065207
swissprot - A0A024RC48
swissprot - Q10472
swissprot - K7EJV8
swissprot - K7EK46
Ensembl - ENSG00000141429
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 galnt1ENSDARG00000061335Danio rerio
 GALNT1ENSGALG00000013135Gallus gallus
 Galnt1ENSMUSG00000000420Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8IUC8 / GALNT13 / polypeptide N-acetylgalactosaminyltransferase 13ENSG0000014427882
GALNT3 / Q14435 / polypeptide N-acetylgalactosaminyltransferase 3ENSG0000011533943
GALNT6 / Q8NCL4 / polypeptide N-acetylgalactosaminyltransferase 6ENSG0000013962943
GALNT4 / Q8N4A0 / polypeptide N-acetylgalactosaminyltransferase 4ENSG0000025759443
Q8NCW6 / GALNT11 / polypeptide N-acetylgalactosaminyltransferase 11ENSG0000017823442
POC1B-GALNT4 / POC1B-GALNT4 readthroughENSG0000025907542
Q8IXK2 / GALNT12 / polypeptide N-acetylgalactosaminyltransferase 12ENSG0000011951441
GALNT2 / Q10471 / polypeptide N-acetylgalactosaminyltransferase 2ENSG0000014364140
Q8N428 / GALNT16 / polypeptide N-acetylgalactosaminyltransferase 16ENSG0000010062637
GALNT5 / Q7Z7M9 / polypeptide N-acetylgalactosaminyltransferase 5ENSG0000013654237
Q96FL9 / GALNT14 / polypeptide N-acetylgalactosaminyltransferase 14ENSG0000015808936
Q7Z4T8 / GALNTL5 / polypeptide N-acetylgalactosaminyltransferase like 5ENSG0000010664831


Protein motifs (from Interpro)
Interpro ID Name
 IPR000772  Ricin B, lectin domain
 IPR001173  Glycosyltransferase 2-like
 IPR029044  Nucleotide-diphospho-sugar transferases
 IPR035992  Ricin B-like lectins


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006486 protein glycosylation IEA
 biological_processGO:0006493 protein O-linked glycosylation TAS
 biological_processGO:0016266 O-glycan processing TAS
 biological_processGO:0018242 protein O-linked glycosylation via serine IDA
 biological_processGO:0018243 protein O-linked glycosylation via threonine IDA
 cellular_componentGO:0000139 Golgi membrane TAS
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0005794 Golgi apparatus IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0032580 Golgi cisterna membrane IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IDA
 molecular_functionGO:0004653 polypeptide N-acetylgalactosaminyltransferase activity TAS
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016757 transferase activity, transferring glycosyl groups IEA
 molecular_functionGO:0030145 manganese ion binding IDA
 molecular_functionGO:0030246 carbohydrate binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
COPI-independent Golgi-to-ER retrograde traffic
O-linked glycosylation of mucins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000104671 DCTN6 / O00399 / dynactin subunit 6  / complex / reaction
 ENSG00000131966 ACTR10 / Q9NZ32 / actin related protein 10 homolog  / complex / reaction
 ENSG00000088986 DYNLL1 / P63167 / dynein light chain LC8-type 1  / complex / reaction
 ENSG00000137100 DCTN3 / O75935 / dynactin subunit 3  / complex / reaction
 ENSG00000135720 O43237 / DYNC1LI2 / dynein cytoplasmic 1 light intermediate chain 2  / complex / reaction
 ENSG00000077549 CAPZB / P47756 / capping actin protein of muscle Z-line beta subunit  / complex / reaction
 ENSG00000116489 CAPZA1 / P52907 / capping actin protein of muscle Z-line alpha subunit 1  / complex / reaction
 ENSG00000144635 Q9Y6G9 / DYNC1LI1 / dynein cytoplasmic 1 light intermediate chain 1  / complex / reaction
 ENSG00000166847 DCTN5 / Q9BTE1 / dynactin subunit 5  / complex / reaction
 ENSG00000151746 BICD1 / Q96G01 / BICD cargo adaptor 1  / complex / reaction
 ENSG00000175582 RAB6A / P20340 / RAB6A, member RAS oncogene family  / complex / reaction
 ENSG00000177938 CAPZA3 / Q96KX2 / capping actin protein of muscle Z-line alpha subunit 3  / complex / reaction
 ENSG00000077380 Q13409 / DYNC1I2 / dynein cytoplasmic 1 intermediate chain 2  / complex / reaction
 ENSG00000158560 O14576 / DYNC1I1 / dynein cytoplasmic 1 intermediate chain 1  / complex / reaction
 ENSG00000204843 DCTN1 / Q14203 / dynactin subunit 1  / complex / reaction
 ENSG00000197102 Q14204 / DYNC1H1 / dynein cytoplasmic 1 heavy chain 1  / complex / reaction
 ENSG00000198898 CAPZA2 / P47755 / capping actin protein of muscle Z-line alpha subunit 2  / complex / reaction
 ENSG00000138107 ACTR1A / P61163 / ARP1 actin related protein 1 homolog A  / complex / reaction
 ENSG00000007168 P43034 / PAFAH1B1 / platelet activating factor acetylhydrolase 1b regulatory subunit 1  / reaction
 ENSG00000132912 DCTN4 / Q9UJW0 / dynactin subunit 4  / complex / reaction
 ENSG00000175203 DCTN2 / Q13561 / dynactin subunit 2  / complex / reaction
 ENSG00000264364 DYNLL2 / Q96FJ2 / dynein light chain LC8-type 2  / complex / reaction






 

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