ENSG00000142544


Homo sapiens

Features
Gene ID: ENSG00000142544
  
Biological name :CTU1
  
Synonyms : CTU1 / cytosolic thiouridylase subunit 1 / Q7Z7A3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: q13.41
Gene start: 51097606
Gene end: 51108370
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSP00000390011
NCBI entrez gene - 90353     See in Manteia.
OMIM - 612694
RefSeq - NM_145232
RefSeq Peptide - NP_660275
swissprot - Q7Z7A3
Ensembl - ENSG00000142544
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ctu1ENSDARG00000020986Danio rerio
 Ctu1ENSMUSG00000038888Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000541  Cytoplasmic tRNA 2-thiolation protein 1
 IPR011063  tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal
 IPR014729  Rossmann-like alpha/beta/alpha sandwich fold
 IPR032442  Cytoplasmic tRNA 2-thiolation protein 1, C-terminal
 IPR035107  tRNA thiolation protein, TtcA/Ctu1 type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002098 tRNA wobble uridine modification NAS
 biological_processGO:0006400 tRNA modification TAS
 biological_processGO:0008033 tRNA processing IEA
 biological_processGO:0034227 tRNA thio-modification NAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0000049 tRNA binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
tRNA modification in the nucleus and cytosol


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000167118 URM1 / Q9BTM9 / ubiquitin related modifier 1  / complex
 ENSG00000174177 CTU2 / Q2VPK5 / cytosolic thiouridylase subunit 2  / complex






 

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