ENSG00000152503


Homo sapiens

Features
Gene ID: ENSG00000152503
  
Biological name :TRIM36
  
Synonyms : Q9NQ86 / TRIM36 / tripartite motif containing 36
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: -1
Band: q22.3
Gene start: 115124762
Gene end: 115180546
  
Corresponding Affymetrix probe sets: 1565812_at (Human Genome U133 Plus 2.0 Array)   1565814_at (Human Genome U133 Plus 2.0 Array)   219736_at (Human Genome U133 Plus 2.0 Array)   231123_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000423934
Ensembl peptide - ENSP00000368938
Ensembl peptide - ENSP00000424259
Ensembl peptide - ENSP00000424743
Ensembl peptide - ENSP00000282369
Ensembl peptide - ENSP00000368937
NCBI entrez gene - 55521     See in Manteia.
OMIM - 609317
RefSeq - XM_017009623
RefSeq - NM_001017397
RefSeq - NM_001017398
RefSeq - NM_001300752
RefSeq - NM_001300759
RefSeq - NM_018700
RefSeq - XM_017009621
RefSeq - XM_017009622
RefSeq Peptide - NP_001017397
RefSeq Peptide - NP_001287688
RefSeq Peptide - NP_061170
RefSeq Peptide - NP_001017398
RefSeq Peptide - NP_001287681
swissprot - E9PBG3
swissprot - D6RAU9
swissprot - Q9NQ86
Ensembl - ENSG00000152503
  
Related genetic diseases (OMIM): 206500 - ?Anencephaly, 206500
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 trim36ENSDARG00000062794Danio rerio
 TRIM36ENSGALG00000008188Gallus gallus
 Q80WG7ENSMUSG00000033949Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q7Z4K8 / TRIM46 / tripartite motif containing 46ENSG0000016346243
MID1 / O15344 / midline 1ENSG0000010187124
MID2 / Q9UJV3 / midline 2ENSG0000008056123
Q6ZTA4 / TRIM67 / tripartite motif containing 67ENSG0000011928323
TRIM9 / Q9C026 / tripartite motif containing 9ENSG0000010050522
Q9BYV6 / TRIM55 / tripartite motif containing 55ENSG0000014757318
Q9BYV2 / TRIM54 / tripartite motif containing 54ENSG0000013810015
FSD1 / Q9BTV5 / fibronectin type III and SPRY domain containing 1ENSG0000010525514
Q969Q1 / TRIM63 / tripartite motif containing 63ENSG0000015802214
FSD1L / Q9BXM9 / fibronectin type III and SPRY domain containing 1 likeENSG0000010670113


Protein motifs (from Interpro)
Interpro ID Name
 IPR000315  B-box-type zinc finger
 IPR001841  Zinc finger, RING-type
 IPR001870  B30.2/SPRY domain
 IPR003879  Butyrophylin-like, SPRY domain
 IPR003961  Fibronectin type III
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR013320  Concanavalin A-like lectin/glucanase domain superfamily
 IPR013783  Immunoglobulin-like fold
 IPR017903  COS domain
 IPR017907  Zinc finger, RING-type, conserved site
 IPR027370  RING-type zinc-finger, LisH dimerisation motif
 IPR027726  E3 ubiquitin-protein ligase Trim36
 IPR035727  TRIM36, PRY/SPRY domain
 IPR036116  Fibronectin type III superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000209 protein polyubiquitination TAS
 biological_processGO:0000281 mitotic cytokinesis IMP
 biological_processGO:0007051 spindle organization IMP
 biological_processGO:0007340 acrosome reaction IEA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0051726 regulation of cell cycle IEA
 biological_processGO:0070507 regulation of microtubule cytoskeleton organization IMP
 cellular_componentGO:0001669 acrosomal vesicle IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0043014 alpha-tubulin binding ISS
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 HP:0002323 Anencephaly 
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 HP:0002414 Spina bifida "Incomplete closure of the embryonic neural tube, whereby some vertebral arches remain unfused and open." [HPO:curators]
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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