ENSG00000157014


Homo sapiens

Features
Gene ID: ENSG00000157014
  
Biological name :TATDN2
  
Synonyms : Q93075 / TatD DNase domain containing 2 / TATDN2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: 1
Band: p25.3
Gene start: 10248023
Gene end: 10281218
  
Corresponding Affymetrix probe sets: 1565580_s_at (Human Genome U133 Plus 2.0 Array)   203648_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000389896
Ensembl peptide - ENSP00000408736
Ensembl peptide - ENSP00000287652
NCBI entrez gene - 9797     See in Manteia.
RefSeq - NM_014760
RefSeq Peptide - NP_055575
swissprot - A0A024R2F3
swissprot - H7BZJ2
swissprot - Q93075
Ensembl - ENSG00000157014
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tatdn2ENSDARG00000070618Danio rerio
 Tatdn2ENSMUSG00000056952Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
AC022384.1ENSG0000027241087
Q6P1N9 / TATDN1 / TatD DNase domain containing 1ENSG000001476879


Protein motifs (from Interpro)
Interpro ID Name
 IPR001130  TatD family
 IPR018228  Deoxyribonuclease, TatD-related, conserved site
 IPR032466  Metal-dependent hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006259 DNA metabolic process IEA
 biological_processGO:0006308 DNA catabolic process IBA
 biological_processGO:0036498 IRE1-mediated unfolded protein response TAS
 biological_processGO:0090305 nucleic acid phosphodiester bond hydrolysis IEA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0016607 nuclear speck IDA
 molecular_functionGO:0004518 nuclease activity IEA
 molecular_functionGO:0004536 deoxyribonuclease activity IBA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016788 hydrolase activity, acting on ester bonds IEA
 molecular_functionGO:0016888 endodeoxyribonuclease activity, producing 5"-phosphomonoesters IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
XBP1(S) activates chaperone genes


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr