ENSG00000158623


Homo sapiens

Features
Gene ID: ENSG00000158623
  
Biological name :COPG2
  
Synonyms : coatomer protein complex subunit gamma 2 / COPG2 / Q9UBF2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: -1
Band: q32.2
Gene start: 130506238
Gene end: 130668748
  
Corresponding Affymetrix probe sets: 223457_at (Human Genome U133 Plus 2.0 Array)   233569_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000402346
Ensembl peptide - ENSP00000331218
NCBI entrez gene - 26958     See in Manteia.
OMIM - 604355
RefSeq - NM_001290033
RefSeq - NM_012133
RefSeq Peptide - NP_001276962
RefSeq Peptide - NP_036265
swissprot - Q9UBF2
swissprot - A0A140VK12
Ensembl - ENSG00000158623
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 copg2ENSDARG00000034823Danio rerio
 COPG2ENSGALG00000008144Gallus gallus
 Copg2ENSMUSG00000025607Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
COPG1 / Q9Y678 / coatomer protein complex subunit gamma 1ENSG0000018178981


Protein motifs (from Interpro)
Interpro ID Name
 IPR002553  Clathrin/coatomer adaptor, adaptin-like, N-terminal
 IPR009028  Coatomer/calthrin adaptor appendage, C-terminal subdomain
 IPR011989  Armadillo-like helical
 IPR013040  Coatomer, gamma subunit, appendage, Ig-like subdomain
 IPR013041  Clathrin adaptor, appendage, Ig-like subdomain superfamily
 IPR016024  Armadillo-type fold
 IPR017106  Coatomer gamma subunit
 IPR032154  Coatomer subunit gamma, C-terminal
 IPR037067  Coatomer, gamma subunit, appendage domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006886 intracellular protein transport IEA
 biological_processGO:0006888 ER to Golgi vesicle-mediated transport TAS
 biological_processGO:0006890 retrograde vesicle-mediated transport, Golgi to ER TAS
 biological_processGO:0006891 intra-Golgi vesicle-mediated transport IDA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016192 vesicle-mediated transport IEA
 cellular_componentGO:0000139 Golgi membrane TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030117 membrane coat IEA
 cellular_componentGO:0030126 COPI vesicle coat IDA
 cellular_componentGO:0030133 transport vesicle TAS
 cellular_componentGO:0030663 COPI-coated vesicle membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 molecular_functionGO:0005198 structural molecule activity IEA
 molecular_functionGO:0005488 binding IEA


Pathways (from Reactome)
Pathway description
COPI-mediated anterograde transport
COPI-dependent Golgi-to-ER retrograde traffic


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000129083 COPB1 / P53618 / coatomer protein complex subunit beta 1  / complex
 ENSG00000122218 COPA / P53621 / coatomer protein complex subunit alpha  / complex
 ENSG00000111481 COPZ1 / P61923 / coatomer protein complex subunit zeta 1  / complex
 ENSG00000138768 USO1 / O60763 / USO1 vesicle transport factor  / complex / reaction
 ENSG00000105669 COPE / O14579 / coatomer protein complex subunit epsilon  / complex
 ENSG00000095139 ARCN1 / P48444 / archain 1  / complex
 ENSG00000168374 ARF4 / P18085 / ADP ribosylation factor 4  / complex / reaction
 ENSG00000174903 RAB1B / Q9H0U4 / RAB1B, member RAS oncogene family  / complex / reaction
 ENSG00000184432 COPB2 / P35606 / coatomer protein complex subunit beta 2  / complex
 ENSG00000107862 GBF1 / Q92538 / golgi brefeldin A resistant guanine nucleotide exchange factor 1  / complex / reaction
 ENSG00000005243 COPZ2 / Q9P299 / coatomer protein complex subunit zeta 2  / complex






 

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