ENSG00000172350


Homo sapiens

Features
Gene ID: ENSG00000172350
  
Biological name :ABCG4
  
Synonyms : ABCG4 / ATP binding cassette subfamily G member 4 / Q9H172
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: 1
Band: q23.3
Gene start: 119149012
Gene end: 119162653
  
Corresponding Affymetrix probe sets: 207593_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000484289
Ensembl peptide - ENSP00000431915
Ensembl peptide - ENSP00000479253
Ensembl peptide - ENSP00000481728
NCBI entrez gene - 64137     See in Manteia.
RefSeq - XM_017018121
RefSeq - NM_001142505
RefSeq - NM_001348191
RefSeq - NM_022169
RefSeq - XM_011542952
RefSeq Peptide - NP_001335120
RefSeq Peptide - NP_071452
RefSeq Peptide - NP_001135977
swissprot - Q9H172
swissprot - E9PJ00
Ensembl - ENSG00000172350
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 abcg4aENSDARG00000061047Danio rerio
 abcg4bENSDARG00000078068Danio rerio
 ABCG4ENSGALG00000006795Gallus gallus
 Abcg4ENSMUSG00000032131Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ABCG1 / P45844 / ATP binding cassette subfamily G member 1ENSG0000016017971
ABCG2 / Q9UNQ0 / ATP binding cassette subfamily G member 2 (Junior blood group)ENSG0000011877726
ABCG5 / Q9H222 / ATP binding cassette subfamily G member 5ENSG0000013807524


Protein motifs (from Interpro)
Interpro ID Name
 IPR003439  ABC transporter-like
 IPR003593  AAA+ ATPase domain
 IPR013525  ABC-2 type transporter
 IPR017871  ABC transporter, conserved site
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0033344 cholesterol efflux TAS
 biological_processGO:0055085 transmembrane transport TAS
 biological_processGO:1990830 cellular response to leukemia inhibitory factor IEA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016887 ATPase activity IEA
 molecular_functionGO:0017127 cholesterol transporter activity TAS
 molecular_functionGO:0034041 sterol-transporting ATPase activity IBA
 molecular_functionGO:0042803 protein homodimerization activity IDA
 molecular_functionGO:0046982 protein heterodimerization activity IPI


Pathways (from Reactome)
Pathway description
ABC transporters in lipid homeostasis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000172350 ABCG4 / Q9H172 / ATP binding cassette subfamily G member 4  / complex






 

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