ENSG00000172955


Homo sapiens

Features
Gene ID: ENSG00000172955
  
Biological name :ADH6
  
Synonyms : ADH6 / alcohol dehydrogenase 6 (class V) / P28332
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: -1
Band: q23
Gene start: 99202638
Gene end: 99219537
  
Corresponding Affymetrix probe sets: 207544_s_at (Human Genome U133 Plus 2.0 Array)   214261_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000425275
Ensembl peptide - ENSP00000378358
Ensembl peptide - ENSP00000426187
Ensembl peptide - ENSP00000378359
Ensembl peptide - ENSP00000422124
Ensembl peptide - ENSP00000237653
NCBI entrez gene - 130     See in Manteia.
OMIM - 103735
RefSeq - NM_000672
RefSeq - NM_001102470
RefSeq Peptide - NP_000663
RefSeq Peptide - NP_001095940
swissprot - P28332
swissprot - D6RH17
swissprot - Q8IUN7
swissprot - D6RDN5
swissprot - A0A0A0MS56
swissprot - H0Y8U2
Ensembl - ENSG00000172955
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 adh5ENSDARG00000080010Danio rerio
 adh8aENSDARG00000091211Danio rerio
 adh8bENSDARG00000024278Danio rerio
 zgc:63568ENSDARG00000087262Danio rerio
 zgc:77938ENSDARG00000088366Danio rerio
 Adh6aENSMUSG00000053054Mus musculus
 Adh6bENSMUSG00000074206Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ADH1B / P00325 / alcohol dehydrogenase 1B (class I), beta polypeptideENSG0000019661664
ADH1A / P07327 / alcohol dehydrogenase 1A (class I), alpha polypeptideENSG0000018775863
ADH1C / P00326 / alcohol dehydrogenase 1C (class I), gamma polypeptideENSG0000024814463
ADH7 / P40394 / alcohol dehydrogenase 7 (class IV), mu or sigma polypeptideENSG0000019634459
ADH4 / P08319 / alcohol dehydrogenase 4 (class II), pi polypeptideENSG0000019809959
ADH5 / P11766 / alcohol dehydrogenase 5 (class III), chi polypeptideENSG0000019789458


Protein motifs (from Interpro)
Interpro ID Name
 IPR002328  Alcohol dehydrogenase, zinc-type, conserved site
 IPR011032  GroES-like superfamily
 IPR013149  Alcohol dehydrogenase, C-terminal
 IPR013154  Alcohol dehydrogenase, N-terminal
 IPR020843  Polyketide synthase, enoylreductase domain
 IPR036291  NAD(P)-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006069 ethanol oxidation TAS
 biological_processGO:0045471 response to ethanol IDA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0004022 alcohol dehydrogenase (NAD) activity IEA
 molecular_functionGO:0004024 alcohol dehydrogenase activity, zinc-dependent EXP
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Ethanol oxidation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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