ENSG00000182132


Homo sapiens

Features
Gene ID: ENSG00000182132
  
Biological name :KCNIP1
  
Synonyms : KCNIP1 / potassium voltage-gated channel interacting protein 1 / Q9NZI2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: 1
Band: q35.1
Gene start: 170353487
Gene end: 170736632
  
Corresponding Affymetrix probe sets: 221307_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000375071
Ensembl peptide - ENSP00000489903
Ensembl peptide - ENSP00000478151
Ensembl peptide - ENSP00000431102
Ensembl peptide - ENSP00000431053
Ensembl peptide - ENSP00000414886
Ensembl peptide - ENSP00000395323
Ensembl peptide - ENSP00000329686
Ensembl peptide - ENSP00000366577
NCBI entrez gene - 30820     See in Manteia.
OMIM - 604660
RefSeq - XM_017009407
RefSeq - NM_001034837
RefSeq - NM_001034838
RefSeq - NM_001278339
RefSeq - NM_001278340
RefSeq - NM_014592
RefSeq Peptide - NP_001265268
RefSeq Peptide - NP_055407
RefSeq Peptide - NP_001030009
RefSeq Peptide - NP_001030010
RefSeq Peptide - NP_001265269
swissprot - A0A1B0GTZ7
swissprot - A0A0C4DFQ7
swissprot - A0A0A0MS16
swissprot - Q9NZI2
swissprot - E5RJY5
swissprot - A0A087WTU8
Ensembl - ENSG00000182132
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 kcnip1bENSDARG00000034808Danio rerio
 KCNIP1ENSGALG00000002132Gallus gallus
 Kcnip1ENSMUSG00000053519Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
KCNIP4 / Q6PIL6 / potassium voltage-gated channel interacting protein 4ENSG0000018577463
KCNIP3 / Q9Y2W7 / potassium voltage-gated channel interacting protein 3ENSG0000011504159
KCNIP2 / Q9NS61 / potassium voltage-gated channel interacting protein 2ENSG0000012004959
NCS1 / P62166 / neuronal calcium sensor 1ENSG0000010713035
VSNL1 / P62760 / visinin like 1ENSG0000016303234
HPCAL1 / P37235 / hippocalcin like 1ENSG0000011575633
HPCA / P84074 / hippocalcinENSG0000012190533
HPCAL4 / Q9UM19 / hippocalcin like 4ENSG0000011698332
NCALD / P61601 / neurocalcin deltaENSG0000010449031
RCVRN / P35243 / recoverinENSG0000010904726
GUCA1B / Q9UMX6 / guanylate cyclase activator 1BENSG0000011259925
GUCA1A / P43080 / guanylate cyclase activator 1AENSG0000004854523
GUCA1C / O95843 / guanylate cyclase activator 1CENSG0000013847220


Protein motifs (from Interpro)
Interpro ID Name
 IPR002048  EF-hand domain
 IPR011992  EF-hand domain pair
 IPR018247  EF-Hand 1, calcium-binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006813 potassium ion transport IEA
 biological_processGO:0034765 regulation of ion transmembrane transport IEA
 biological_processGO:0061337 cardiac conduction TAS
 biological_processGO:0065009 regulation of molecular function IEA
 biological_processGO:0071805 potassium ion transmembrane transport IEA
 biological_processGO:1901379 regulation of potassium ion transmembrane transport IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0008076 voltage-gated potassium channel complex IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0031234 extrinsic component of cytoplasmic side of plasma membrane IDA
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0005244 voltage-gated ion channel activity IEA
 molecular_functionGO:0005267 potassium channel activity IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0015459 potassium channel regulator activity IDA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Phase 1 - inactivation of fast Na+ channels


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000120049 KCNIP2 / Q9NS61 / potassium voltage-gated channel interacting protein 2  / complex
 ENSG00000115041 KCNIP3 / Q9Y2W7 / potassium voltage-gated channel interacting protein 3  / complex
 ENSG00000102057 KCND1 / Q9NSA2 / potassium voltage-gated channel subfamily D member 1  / complex
 ENSG00000171385 KCND3 / Q9UK17 / potassium voltage-gated channel subfamily D member 3  / complex
 ENSG00000182132 KCNIP1 / Q9NZI2 / potassium voltage-gated channel interacting protein 1  / complex
 ENSG00000184408 KCND2 / Q9NZV8 / potassium voltage-gated channel subfamily D member 2  / complex
 ENSG00000185774 KCNIP4 / Q6PIL6 / potassium voltage-gated channel interacting protein 4  / complex






 

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