ENSG00000186867


Homo sapiens

Features
Gene ID: ENSG00000186867
  
Biological name :QRFPR
  
Synonyms : pyroglutamylated RFamide peptide receptor / Q96P65 / QRFPR
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: -1
Band: q27
Gene start: 121329312
Gene end: 121381059
  
Corresponding Affymetrix probe sets: 1555533_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000335610
Ensembl peptide - ENSP00000377948
Ensembl peptide - ENSP00000423369
NCBI entrez gene - 84109     See in Manteia.
OMIM - 606925
RefSeq - XM_017008693
RefSeq - NM_198179
RefSeq Peptide - NP_937822
swissprot - F2Z3L3
swissprot - Q96P65
swissprot - J3KNR3
Ensembl - ENSG00000186867
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 QRFPRENSDARG00000101969Danio rerio
 qrfpraENSDARG00000039349Danio rerio
 QRFPRENSGALG00000037740Gallus gallus
 C130060K24RikENSMUSG00000029917Mus musculus
 QrfprENSMUSG00000058400Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NPFFR2 / Q9Y5X5 / neuropeptide FF receptor 2ENSG0000005629127
NPFFR1 / Q9GZQ6 / neuropeptide FF receptor 1ENSG0000014873424
HCRTR2 / O43614 / hypocretin receptor 2ENSG0000013725223
CCKAR / P32238 / cholecystokinin A receptorENSG0000016339423
HCRTR1 / O43613 / hypocretin receptor 1ENSG0000012176422
GALR1 / P47211 / galanin receptor 1ENSG0000016657321
CCKBR / P32239 / cholecystokinin B receptorENSG0000011014820
KISS1R / Q969F8 / KISS1 receptorENSG0000011601419
GALR3 / O60755 / galanin receptor 3ENSG0000012831019
GALR2 / O43603 / galanin receptor 2ENSG0000018268717


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR000611  Neuropeptide Y receptor family
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007218 neuropeptide signaling pathway IEA
 biological_processGO:0032870 cellular response to hormone stimulus IBA
 biological_processGO:1901652 response to peptide IBA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0004983 neuropeptide Y receptor activity IEA
 molecular_functionGO:0042277 peptide binding IBA


Pathways (from Reactome)
Pathway description
Orexin and neuropeptides FF and QRFP bind to their respective receptors
G alpha (q) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000188710 QRFP / P83859 / pyroglutamylated RFamide peptide  / complex / reaction






 

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