ENSG00000198077


Homo sapiens

Features
Gene ID: ENSG00000198077
  
Biological name :CYP2A7
  
Synonyms : CYP2A7 / cytochrome P450 family 2 subfamily A member 7 / P20853
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: q13.2
Gene start: 40875439
Gene end: 40882752
  
Corresponding Affymetrix probe sets: 1494_f_at (Human Genome U133 Plus 2.0 Array)   207718_x_at (Human Genome U133 Plus 2.0 Array)   211295_x_at (Human Genome U133 Plus 2.0 Array)   214320_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000291764
Ensembl peptide - ENSP00000301146
Ensembl peptide - ENSP00000470933
NCBI entrez gene - 1549     See in Manteia.
OMIM - 608054
RefSeq - XM_017026383
RefSeq - NM_000764
RefSeq - NM_030589
RefSeq Peptide - NP_000755
RefSeq Peptide - NP_085079
swissprot - F8W816
swissprot - M0R020
swissprot - P20853
Ensembl - ENSG00000198077
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CYP2C9ENSDARG00000101423Danio rerio
 Cyp2a4ENSMUSG00000074254Mus musculus
 Cyp2a5ENSMUSG00000005547Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CYP2A6 / P11509 / cytochrome P450 family 2 subfamily A member 6ENSG0000025597494
Q16696 / CYP2A13 / cytochrome P450 family 2 subfamily A member 13ENSG0000019783891
CYP2B6 / P20813 / cytochrome P450 family 2 subfamily B member 6ENSG0000019740851
CYP2F1 / P24903 / cytochrome P450 family 2 subfamily F member 1ENSG0000019744650
CYP2C8 / P10632 / cytochrome P450 family 2 subfamily C member 8ENSG0000013811549
P33261 / CYP2C19 / cytochrome P450 family 2 subfamily C member 19ENSG0000016584149
P33260 / CYP2C18 / cytochrome P450 family 2 subfamily C member 18ENSG0000010824248
CYP2C9 / P11712 / cytochrome P450 family 2 subfamily C member 9ENSG0000013810948
CYP2E1 / P05181 / cytochrome P450 family 2 subfamily E member 1ENSG0000013064946
AL583836.1ENSG0000027649029


Protein motifs (from Interpro)
Interpro ID Name
 IPR001128  Cytochrome P450
 IPR002401  Cytochrome P450, E-class, group I
 IPR008067  Cytochrome P450, E-class, group I, CYP2A-like
 IPR017972  Cytochrome P450, conserved site
 IPR036396  Cytochrome P450 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0019373 epoxygenase P450 pathway IBA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031090 organelle membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0004497 monooxygenase activity IEA
 molecular_functionGO:0005506 iron ion binding IEA
 molecular_functionGO:0008392 arachidonic acid epoxygenase activity IBA
 molecular_functionGO:0008395 steroid hydroxylase activity IBA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
 molecular_functionGO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen IEA
 molecular_functionGO:0019825 oxygen binding TAS
 molecular_functionGO:0020037 heme binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0070330 aromatase activity IEA


Pathways (from Reactome)
Pathway description
Fatty acids
Xenobiotics
CYP2E1 reactions


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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