ENSG00000211640


Homo sapiens

Features
Gene ID: ENSG00000211640
  
Biological name :IGLV6-57
  
Synonyms : IGLV6-57 / immunoglobulin lambda variable 6-57 / P01721
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 22
Strand: 1
Band: q11.22
Gene start: 22195799
Gene end: 22196276
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSP00000374820
swissprot - P01721
Ensembl - ENSG00000211640
  
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000039268Gallus gallus
 ENSGALG00000034721Gallus gallus
 ENSGALG00000005937Gallus gallus
 ENSGALG00000030653Gallus gallus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P01703 / IGLV1-40 / immunoglobulin lambda variable 1-40ENSG0000021165370
IGLV2-18 / A0A075B6J9 / immunoglobulin lambda variable 2-18ENSG0000021166468
P01700 / IGLV1-47 / immunoglobulin lambda variable 1-47ENSG0000021164867
P01699 / IGLV1-44 / immunoglobulin lambda variable 1-44ENSG0000021165167
IGLV1-50 / immunoglobulin lambda variable 1-50 (non-functional)ENSG0000021164566
P01704 / IGLV2-14 / immunoglobulin lambda variable 2-14ENSG0000021166666
P01706 / IGLV2-11 / immunoglobulin lambda variable 2-11ENSG0000021166866
P01709 / IGLV2-8 / immunoglobulin lambda variable 2-8ENSG0000027819666
P01701 / IGLV1-51 / immunoglobulin lambda variable 1-51ENSG0000021164465
P01705 / IGLV2-23 / immunoglobulin lambda variable 2-23ENSG0000021166065
IGLV1-36 / A0A0B4J1U3 / immunoglobulin lambda variable 1-36ENSG0000021165564
P01717 / IGLV3-25 / immunoglobulin lambda variable 3-25ENSG0000021165961
IGLV3-10 / A0A075B6K4 / immunoglobulin lambda variable 3-10ENSG0000021166961
P01714 / IGLV3-19 / immunoglobulin lambda variable 3-19ENSG0000021166360
IGLV3-9 / A0A075B6K5 / immunoglobulin lambda variable 3-9 (gene/pseudogene)ENSG0000021167058
P01715 / IGLV3-1 / immunoglobulin lambda variable 3-1ENSG0000021167358
IGLV2-33 / immunoglobulin lambda variable 2-33 (non-functional)ENSG0000021165657
P80748 / IGLV3-21 / immunoglobulin lambda variable 3-21ENSG0000021166257
IGLV3-16 / A0A075B6K0 / immunoglobulin lambda variable 3-16ENSG0000021166557
P01718 / IGLV3-27 / immunoglobulin lambda variable 3-27ENSG0000021165856


Protein motifs (from Interpro)
Interpro ID Name
No match


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002250 adaptive immune response IEA
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006898 receptor-mediated endocytosis TAS
 biological_processGO:0006955 immune response NAS
 biological_processGO:0006956 complement activation TAS
 biological_processGO:0006958 complement activation, classical pathway TAS
 biological_processGO:0030449 regulation of complement activation TAS
 biological_processGO:0038095 Fc-epsilon receptor signaling pathway TAS
 biological_processGO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis TAS
 biological_processGO:0050776 regulation of immune response TAS
 biological_processGO:0050900 leukocyte migration TAS
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003823 antigen binding NAS
 molecular_functionGO:0004252 serine-type endopeptidase activity TAS


Pathways (from Reactome)
Pathway description
Initial triggering of complement
Classical antibody-mediated complement activation
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Cell surface interactions at the vascular wall
FCGR activation
Regulation of actin dynamics for phagocytic cup formation
Role of phospholipids in phagocytosis
Scavenging of heme from plasma
Fc epsilon receptor (FCERI) signaling
Role of LAT2/NTAL/LAB on calcium mobilization
FCERI mediated MAPK activation
FCERI mediated Ca+2 mobilization
FCERI mediated NF-kB activation
CD22 mediated BCR regulation
Regulation of Complement cascade
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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