ENSG00000260027


Homo sapiens

Features
Gene ID: ENSG00000260027
  
Biological name :HOXB7
  
Synonyms : homeobox B7 / HOXB7 / P09629
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: q21.32
Gene start: 48607227
Gene end: 48633572
  
Corresponding Affymetrix probe sets: 204778_x_at (Human Genome U133 Plus 2.0 Array)   204779_s_at (Human Genome U133 Plus 2.0 Array)   216973_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000239165
NCBI entrez gene - 3217     See in Manteia.
OMIM - 142962
RefSeq - NM_004502
RefSeq Peptide - NP_004493
swissprot - P09629
Ensembl - ENSG00000260027
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 HOXB7ENSGALG00000032740Gallus gallus
 Hoxb7ENSMUSG00000038721Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HOXA7 / P31268 / homeobox A7ENSG0000012259259
HOXB6 / P17509 / homeobox B6ENSG0000010851147
HOXA6 / P31267 / homeobox A6ENSG0000010600641
HOXB5 / P09067 / homeobox B5ENSG0000012007541
HOXA5 / P20719 / homeobox A5ENSG0000010600439
HOXD8 / P13378 / homeobox D8ENSG0000017587938
HOXB8 / P17481 / homeobox B8ENSG0000012006837
HOXD4 / P09016 / homeobox D4ENSG0000017016637
HOXC6 / P09630 / homeobox C6ENSG0000019775737
HOXC8 / P31273 / homeobox C8ENSG0000003796536
HOXB4 / P17483 / homeobox B4ENSG0000018274236
HOXC5 / Q00444 / homeobox C5ENSG0000017278935
HOXA4 / Q00056 / homeobox A4ENSG0000019757635
HOXC4 / P09017 / homeobox C4ENSG0000019835335
CDX1 / P47902 / caudal type homeobox 1ENSG0000011372229
AC012531.3ENSG0000027304928
CDX4 / O14627 / caudal type homeobox 4ENSG0000013126425
CDX2 / Q99626 / caudal type homeobox 2ENSG0000016555625


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR001827  Homeobox protein, antennapedia type, conserved site
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site
 IPR017995  Homeobox protein, antennapedia type
 IPR020479  Homeobox domain, metazoa


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated NAS
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0007275 multicellular organism development NAS
 biological_processGO:0009952 anterior/posterior pattern specification IEA
 biological_processGO:0030099 myeloid cell differentiation IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 biological_processGO:0048704 embryonic skeletal system morphogenesis IEA
 biological_processGO:0090190 positive regulation of branching involved in ureteric bud morphogenesis IEA
 cellular_componentGO:0005634 nucleus NAS
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0016604 nuclear body IDA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity NAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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