ENSGALG00000000525


Gallus gallus

Features
Gene ID: ENSGALG00000000525
  
Biological name :MAP3K3
  
Synonyms : MAP3K3 / mitogen-activated protein kinase kinase kinase 3
  
Possible biological names infered from orthology : Q61084 / Q99759
  
Species: Gallus gallus
  
Chr. number: 27
Strand: 1
Band:
Gene start: 2906874
Gene end: 2941579
  
Corresponding Affymetrix probe sets: Gga.10835.1.S1_at (Chicken Array)   Gga.16532.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000039708
NCBI entrez gene - 419954     See in Manteia.
RefSeq - XM_015299375
RefSeq - XM_015299376
RefSeq - XM_015299377
swissprot - F1NYQ2
Ensembl - ENSGALG00000000525
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 map3k3ENSDARG00000060348Danio rerio
 MAP3K3ENSG00000198909Homo sapiens
 Map3k3ENSMUSG00000020700Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MAPKKK3LENSGALG0000000588460
MAP3K1 / mitogen-activated protein kinase kinase kinase 1 / Q13233*ENSGALG0000001471827
MAP3K19 / mitogen-activated protein kinase kinase kinase 19 / E9Q3S4* / Q56UN5*ENSGALG0000002845724
MAP3K2* / Q9Y2U5* / mitogen-activated protein kinase kinase kinase 2*ENSGALG0000001150219
MAP3K14 / mitogen-activated protein kinase kinase kinase 14 / Q99558* / Q9WUL6*ENSGALG0000000068518
MAP3K8 / mitogen-activated protein kinase kinase kinase 8 / P41279* / Q07174*ENSGALG0000000735617


Protein motifs (from Interpro)
Interpro ID Name
 IPR000270  PB1 domain
 IPR000719  Protein kinase domain
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001568 blood vessel development IEA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007346 regulation of mitotic cell cycle IBA
 biological_processGO:0023014 signal transduction by protein phosphorylation IBA
 biological_processGO:0031098 stress-activated protein kinase signaling cascade IBA
 biological_processGO:0032147 activation of protein kinase activity IBA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0042981 regulation of apoptotic process IBA
 biological_processGO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling IEA
 biological_processGO:0046777 protein autophosphorylation IEA
 biological_processGO:0071864 positive regulation of cell proliferation in bone marrow IEA
 biological_processGO:0090050 positive regulation of cell migration involved in sprouting angiogenesis IEA
 biological_processGO:1900745 positive regulation of p38MAPK cascade IEA
 biological_processGO:2000773 negative regulation of cellular senescence IEA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IBA
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
Interleukin-1 signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000007932 TRAF6 / TNF receptor associated factor 6 / P70196* / Q9Y4K3*  / complex / reaction






 

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