ENSGALG00000001320


Gallus gallus

Features
Gene ID: ENSGALG00000001320
  
Biological name :CYP1A2
  
Synonyms : CYP1A2 / cytochrome P450 1A5
  
Possible biological names infered from orthology : CYP1A1 / Cytochrome P450 1A1 / Cytochrome P450 1A2 / cytochrome P450 family 1 subfamily A member 1 / cytochrome P450 family 1 subfamily A member 2 / P00184 / P00186 / P04798 / P05177
  
Species: Gallus gallus
  
Chr. number: 10
Strand: -1
Band:
Gene start: 2370952
Gene end: 2373767
  
Corresponding Affymetrix probe sets: Gga.617.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000002016
NCBI entrez gene - 396051     See in Manteia.
RefSeq - NM_205146
RefSeq - XM_015278761
RefSeq Peptide - NP_990477
swissprot - F1NMG8
Ensembl - ENSGALG00000001320
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cyp1aENSDARG00000098315Danio rerio
 CYP1A1ENSG00000140465Homo sapiens
 CYP1A2ENSG00000140505Homo sapiens
 Cyp1a1ENSMUSG00000032315Mus musculus
 Cyp1a2ENSMUSG00000032310Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CYP1A1 / cytochrome P450 1A4 / P05177* / CYP1A2* / P00184* / P00186* / P04798* / Cytochrome P450 1A1 * / Cytochrome P450 1A2 * / cytochrome P450 family 1 subfamily A member 1* / cytochrome...ENSGALG0000000132578
CYP1B1 / cytochrome P450 family 1 subfamily B member 1 / Q16678* / Q64429* / Cytochrome P450 1B1 *ENSGALG0000002582237
CYP1C1ENSGALG0000004075436
CYP17A1 / steroid 17-alpha-hydroxylase/17,20 lyase precursor / P05093* / P27786* / Steroid 17-alpha-hydroxylase/17,20 lyase * / cytochrome P450 family 17 subfamily A member 1*ENSGALG0000000812130
CYP2AB4 / Gallus gallus cytochrome P450, family 2, subfamily AB, polypeptide 4 (CYP2AB4), mRNA. / Cyp2ab1* / cytochrome P450, family 2, subfamily ab, polypeptide 1*ENSGALG0000000810526
CYP2AB2 / Gallus gallus cytochrome P450, family 2, subfamily AB, polypeptide 2 (CYP2AB2), mRNA. / Cyp2ab1* / cytochrome P450, family 2, subfamily ab, polypeptide 1*ENSGALG0000000817826
CYP2AB5 / Gallus gallus cytochrome P450, family 2, subfamily AB, polypeptide 5 (CYP2AB5), mRNA. / Cyp2ab1* / cytochrome P450, family 2, subfamily ab, polypeptide 1*ENSGALG0000004525526
CYP2AB3 / Gallus gallus cytochrome P450, family 2, subfamily AB, polypeptide 3 (CYP2AB3), mRNA. / Cyp2ab1* / cytochrome P450, family 2, subfamily ab, polypeptide 1*ENSGALG0000004535126
CYP2AB1 / Gallus gallus cytochrome P450, family 2, subfamily AB, polypeptide 1 (CYP2AB1), mRNA. / cytochrome P450, family 2, subfamily ab, polypeptide 1*ENSGALG0000000828323
CYP21A1 / steroid 21-hydroxylase precursor / P08686* / CYP21A2* / cytochrome P450 family 21 subfamily A member 2*ENSGALG0000003974222


Protein motifs (from Interpro)
Interpro ID Name
 IPR001128  Cytochrome P450
 IPR002401  Cytochrome P450, E-class, group I
 IPR008066  Cytochrome P450, E-class, group I, CYP1
 IPR017972  Cytochrome P450, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0017144 drug metabolic process IMP
 biological_processGO:0043385 mycotoxin metabolic process IDA
 biological_processGO:0046677 response to antibiotic IMP
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0070989 oxidative demethylation IDA
 biological_processGO:0071615 oxidative deethylation IDA
 cellular_componentGO:0005623 cell IDA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0004497 monooxygenase activity IBA
 molecular_functionGO:0005506 iron ion binding IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
 molecular_functionGO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen IEA
 molecular_functionGO:0019825 oxygen binding IDA
 molecular_functionGO:0020037 heme binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0070330 aromatase activity IEA


Pathways (from Reactome)
Pathway description
Methylation
Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2
Xenobiotics
Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET)
Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE)
Aflatoxin activation and detoxification
Biosynthesis of protectins
Biosynthesis of maresin-like SPMs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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