ENSGALG00000003293


Gallus gallus

Features
Gene ID: ENSGALG00000003293
  
Biological name :MBTPS1
  
Synonyms : MBTPS1 / membrane bound transcription factor peptidase, site 1
  
Possible biological names infered from orthology : Membrane-bound transcription factor site-1 protease / Q14703 / Q9WTZ2
  
Species: Gallus gallus
  
Chr. number: 11
Strand: 1
Band:
Gene start: 2563345
Gene end: 2589694
  
Corresponding Affymetrix probe sets: Gga.6187.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000005207
NCBI entrez gene - 415704     See in Manteia.
RefSeq - XM_003641897
swissprot - E1C6Y2
Ensembl - ENSGALG00000003293
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mbtps1ENSDARG00000014634Danio rerio
 MBTPS1ENSG00000140943Homo sapiens
 Mbtps1ENSMUSG00000031835Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000209  Peptidase S8/S53 domain
 IPR015500  Peptidase S8, subtilisin-related
 IPR022398  Peptidase S8, subtilisin, His-active site
 IPR023828  Peptidase S8, subtilisin, Ser-active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0007040 lysosome organization IEA
 biological_processGO:0042990 obsolete regulation of transcription factor import into nucleus IEA
 cellular_componentGO:0005795 Golgi stack IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004175 endopeptidase activity IEA
 molecular_functionGO:0004252 serine-type endopeptidase activity IEA


Pathways (from Reactome)
Pathway description
Regulation of cholesterol biosynthesis by SREBP (SREBF)
ATF6 (ATF6-alpha) activates chaperones
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
CREB3 factors activate genes
Post-translational protein phosphorylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000001252 CREB3L3 / cAMP responsive element binding protein 3 like 3 / Q68CJ9* / Q91XE9* / Cyclic AMP-responsive element-binding protein 3-like protein 3 Processed cyclic AMP-responsive element-bindi...  / reaction
 ENSGALG00000002523 CREB3 / cAMP responsive element binding protein 3 / O43889*  / reaction
 ENSGALG00000041687 SREBF2 / sterol regulatory element binding transcription factor 2 / Q12772* / Q3U1N2* / sterol regulatory element binding factor 2*  / reaction
 ENSGALG00000032278 ATF6 / activating transcription factor 6 / F6VAN0* / P18850* / Cyclic AMP-dependent transcription factor ATF-6 alpha Processed cyclic AMP-dependent transcription factor ATF-6 alpha*  / reaction






 

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