ENSGALG00000032278


Gallus gallus

Features
Gene ID: ENSGALG00000032278
  
Biological name :ATF6
  
Synonyms : activating transcription factor 6 / ATF6
  
Possible biological names infered from orthology : Cyclic AMP-dependent transcription factor ATF-6 alpha Processed cyclic AMP-dependent transcription factor ATF-6 alpha / F6VAN0 / P18850
  
Species: Gallus gallus
  
Chr. number: 8
Strand: 1
Band:
Gene start: 3720750
Gene end: 3789997
  
Corresponding Affymetrix probe sets: Gga.10868.1.S1_s_at (Chicken Array)   GgaAffx.25566.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000043808
NCBI entrez gene - 424365     See in Manteia.
RefSeq - XM_015290399
RefSeq - XM_422208
swissprot - A0A1D5NU01
Ensembl - ENSGALG00000032278
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 atf6ENSDARG00000012656Danio rerio
 ATF6ENSG00000118217Homo sapiens
 Atf6ENSMUSG00000026663Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR004827  Basic-leucine zipper domain
 IPR029801  cAMP-dependent transcription factor ATF-6 alpha


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001654 eye development IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007601 visual perception IEA
 biological_processGO:0030968 endoplasmic reticulum unfolded protein response IEA
 biological_processGO:0043065 positive regulation of apoptotic process IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:1903893 positive regulation of ATF6-mediated unfolded protein response IEA
 biological_processGO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030176 integral component of endoplasmic reticulum membrane IEA
 molecular_functionGO:0000976 transcription regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0035497 cAMP response element binding IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity IEA


Pathways (from Reactome)
Pathway description
ATF6 (ATF6-alpha) activates chaperones


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000003293 MBTPS1 / membrane bound transcription factor peptidase, site 1 / Q14703* / Q9WTZ2* / Membrane-bound transcription factor site-1 protease *  / reaction
 ENSGALG00000016382 MBTPS2 / membrane bound transcription factor peptidase, site 2 / Q8CHX6* / O43462* / Q3TTC2* / Membrane-bound transcription factor site-2 protease *  / reaction
 ENSGALG00000001000 HSPA5 / Q90593 / 78 kDa glucose-regulated protein / P11021* / P20029* / heat shock protein 5* / heat shock protein family A (Hsp70) member 5*  / complex






 

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