ENSGALG00000004582


Gallus gallus

Features
Gene ID: ENSGALG00000004582
  
Biological name :MYL2
  
Synonyms : MYL2 / myosin light chain 2
  
Possible biological names infered from orthology : Myosin regulatory light chain 2, ventricular/cardiac muscle isoform / P10916 / P51667
  
Species: Gallus gallus
  
Chr. number: 15
Strand: -1
Band:
Gene start: 6081766
Gene end: 6085776
  
Corresponding Affymetrix probe sets: Gga.841.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000034439
NCBI entrez gene - 416874     See in Manteia.
RefSeq - NM_001271929
RefSeq Peptide - NP_001258858
swissprot - F1NYU0
Ensembl - ENSGALG00000004582
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CABZ01076669.1ENSDARG00000104722Danio rerio
 myl2bENSDARG00000053424Danio rerio
 MYL2ENSG00000111245Homo sapiens
 Myl2ENSMUSG00000013936Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MYL10 / myosin light chain 10 / Q62082* / Q9BUA6* / Myosin regulatory light chain 10 *ENSGALG0000000179387
P24032 / MYL12A / Myosin regulatory light chain 2, smooth muscle minor isoform / Q3THE2* / MYL12B* / O14950* / myosin light chain 12B* / Myosin regulatory light chain 12B *ENSGALG0000001485455
O14950* / Myl12a* / MYL12B* / Q3THE2* / myosin light chain 12B* / Myosin regulatory light chain 12B *ENSGALG0000003863555
MYL9 / P02612 / Myosin regulatory light chain 2, smooth muscle major isoform / Q9CQ19* / Myosin regulatory light polypeptide 9 *ENSGALG0000002856753


Protein motifs (from Interpro)
Interpro ID Name
 IPR002048  EF-hand domain
 IPR011992  EF-hand domain pair
 IPR018247  EF-Hand 1, calcium-binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003007 heart morphogenesis IEA
 biological_processGO:0007507 heart development IEA
 biological_processGO:0009791 post-embryonic development IEA
 biological_processGO:0030308 negative regulation of cell growth IEA
 biological_processGO:0042694 muscle cell fate specification IEA
 biological_processGO:0048747 muscle fiber development IEA
 biological_processGO:0055003 cardiac myofibril assembly IEA
 biological_processGO:0055010 ventricular cardiac muscle tissue morphogenesis IEA
 biological_processGO:0060047 heart contraction IEA
 biological_processGO:0060048 cardiac muscle contraction IEA
 biological_processGO:0098735 positive regulation of the force of heart contraction IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0015629 actin cytoskeleton IEA
 cellular_componentGO:0030016 myofibril IEA
 cellular_componentGO:0097512 cardiac myofibril IEA
 molecular_functionGO:0003785 actin monomer binding IEA
 molecular_functionGO:0005509 calcium ion binding IEA


Pathways (from Reactome)
Pathway description
Striated Muscle Contraction


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000002907 MYL1 / P02605 / P02604 / Myosin light chain 1, skeletal muscle isoform / P05976* / P05977* / myosin light chain 1* / Myosin light chain 1/3, skeletal muscle isoform *  / complex
 ENSGALG00000005448 MYL3 / myosin light chain 1, cardiac muscle / P08590* / P09542* / myosin light chain 3*  / complex
 ENSGALG00000004582 MYL2 / myosin light chain 2 / P10916* / P51667* / Myosin regulatory light chain 2, ventricular/cardiac muscle isoform *  / complex






 

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