ENSGALG00000006270


Gallus gallus
sodiumSCNN1Gchannelionmembraneepithelialtransportplasmaactivityhomeostasisintegralcomponentchordatesconservedsitetransmembranemulticellularorganismalwaternucleoplasmexternalsidecomplexextracellularexosomeligand-gatedwwdomainbindingstimuli-sensingchannels

Features
Gene ID: ENSGALG00000006270
  
Biological name :SCNN1G
  
Synonyms : SCNN1G / sodium channel epithelial 1 gamma subunit
  
Possible biological names infered from orthology : Amiloride-sensitive sodium channel subunit gamma / P51170 / Q9WU39
  
Species: Gallus gallus
  
Chr. number: 14
Strand: -1
Band:
Gene start: 7019086
Gene end: 7028500
  
Corresponding Affymetrix probe sets: Gga.5369.1.S1_at (Chicken Array)   Gga.5369.2.S1_at (Chicken Array)   Gga.5369.2.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000010120
Ensembl peptide - ENSGALP00000056112
NCBI entrez gene - 416579     See in Manteia.
RefSeq - XM_015294500
swissprot - A0A1D5PT70
swissprot - F1NW62
Ensembl - ENSGALG00000006270
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 P51170ENSG00000166828Homo sapiens
 Q9WU39ENSMUSG00000000216Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SCNN1B / sodium channel epithelial 1 beta subunit / P51168* / Q9WU38* / sodium channel, nonvoltage-gated 1 beta*ENSGALG0000000620234
SCNN1A / amiloride-sensitive sodium channel subunit alpha / P37088* / sodium channel, nonvoltage-gated 1 alpha* / sodium channel epithelial 1 alpha subunit*ENSGALG0000004042431
SCNN1D / sodium channel epithelial 1 delta subunit / P51172*ENSGALG0000000183526
ASIC1 / Q1XA76 / Acid-sensing ion channel 1 / P78348* / Q6NXK8* / acid sensing ion channel subunit 1*ENSGALG0000003402519
ASIC2 / acid sensing ion channel subunit 2 / Q16515* / Q925H0* / Acid-sensing ion channel 2 *ENSGALG0000000036718
ASIC4 / acid sensing ion channel subunit family member 4 / Q7TNS7* / Q96FT7* / Acid-sensing ion channel 4 *ENSGALG0000001125018
ASIC5 / acid sensing ion channel subunit family member 5 / Q9NY37* / Q9R0Y1* / Acid-sensing ion channel 5 *ENSGALG000000093669
ENSGALG000000198246


Protein motifs (from Interpro)
Interpro ID Name
 IPR001873  Epithelial sodium channel
 IPR004724  Epithelial sodium channel, chordates
 IPR020903  Epithelial sodium channel, conserved site


Gene Ontology (GO)
establishment of localizationregulation of biological qualityestablishment of localizationregulation of biological qualityestablishment of localizationregulation of biological qualityestablishment of localizationregulation of biological qualityestablishment of localizationregulation of biological qualityestablishment of localizationregulation of biological qualityestablishment of localizationregulation of biological qualityestablishment of localizationregulation of biological qualityestablishment of localizationregulation of biological qualityestablishment of localizationregulation of biological qualityestablishment of localizationestablishment of localizationregulation of biological qualityregulation of biological quality
transmembrane transporter activityprotein bindingtransmembrane transporter activityprotein bindingtransmembrane transporter activityprotein bindingtransmembrane transporter activityprotein bindingtransmembrane transporter activityprotein bindingtransmembrane transporter activityprotein bindingtransmembrane transporter activityprotein bindingtransmembrane transporter activityprotein bindingtransmembrane transporter activityprotein bindingtransmembrane transporter activityprotein bindingtransmembrane transporter activitytransmembrane transporter activityprotein bindingprotein binding
cellorganellemembrane-enclosed lumenmembraneprotein-containing complexextracellular regioncellorganellemembrane-enclosed lumenmembraneprotein-containing complexextracellular regioncellorganellemembrane-enclosed lumenmembraneprotein-containing complexextracellular regioncellorganellemembrane-enclosed lumenmembraneprotein-containing complexextracellular regioncellorganellemembrane-enclosed lumenmembraneprotein-containing complexextracellular regioncellorganellemembrane-enclosed lumenmembraneprotein-containing complexextracellular regioncellorganellemembrane-enclosed lumenmembraneprotein-containing complexextracellular regioncellorganellemembrane-enclosed lumenmembraneprotein-containing complexextracellular regioncellorganellemembrane-enclosed lumenmembraneprotein-containing complexextracellular regioncellorganellemembrane-enclosed lumenmembraneprotein-containing complexextracellular regioncellcellorganelleorganellemembrane-enclosed lumenmembrane-enclosed lumenmembranemembraneprotein-containing compprotein-containing complexextracellular regionextracellular region
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006814 sodium ion transport IEA
 biological_processGO:0035725 sodium ion transmembrane transport IEA
 biological_processGO:0050891 multicellular organismal water homeostasis IEA
 biological_processGO:0055078 sodium ion homeostasis IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0009897 external side of plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0034706 sodium channel complex IEA
 cellular_componentGO:0070062 extracellular exosome IEA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005272 sodium channel activity IEA
 molecular_functionGO:0015280 ligand-gated sodium channel activity IEA
 molecular_functionGO:0050699 WW domain binding IEA


Pathways (from Reactome)
Pathway description
Stimuli-sensing channels


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000037716 UBA52 / ubiquitin A-52 residue ribosomal protein fusion product 1 / P62984* / P62987* / Gm5239* / Gm11808* / predicted gene 11808*  / reaction
 ENSGALG00000040424 SCNN1A / amiloride-sensitive sodium channel subunit alpha / P37088* / sodium channel, nonvoltage-gated 1 alpha* / sodium channel epithelial 1 alpha subunit*  / complex
 ENSGALG00000036790 P79781 / RPS27A / Ubiquitin-40S ribosomal protein S27a Ubiquitin 40S ribosomal protein S27a / P62983* / P62979* / AL136454.1* / ribosomal protein S27a*  / reaction






 

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