ENSGALG00000034025


Gallus gallus

Features
Gene ID: ENSGALG00000034025
  
Biological name :ASIC1
  
Synonyms : Acid-sensing ion channel 1 / ASIC1 / Q1XA76
  
Possible biological names infered from orthology : acid sensing ion channel subunit 1 / P78348 / Q6NXK8
  
Species: Gallus gallus
  
Chr. number: 33
Strand: -1
Band:
Gene start: 296754
Gene end: 327900
  
Corresponding Affymetrix probe sets: Gga.17954.1.S1_s_at (Chicken Array)   GgaAffx.11254.1.S1_at (Chicken Array)   GgaAffx.21877.3.S1_at (Chicken Array)   GgaAffx.21877.3.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000049633
Ensembl peptide - ENSGALP00000057289
Ensembl peptide - ENSGALP00000046681
NCBI entrez gene - 426883     See in Manteia.
RefSeq - XM_015300235
RefSeq - NM_001040467
RefSeq - XM_015300232
RefSeq - XM_015300233
RefSeq - XM_015300234
RefSeq Peptide - NP_001035557
swissprot - A0A1D5PA73
swissprot - A0A1D5P1Y7
swissprot - Q1XA76
Ensembl - ENSGALG00000034025
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 asic1aENSDARG00000008329Danio rerio
 si:dkey-57c15.1ENSDARG00000105115Danio rerio
 ASIC1ENSG00000110881Homo sapiens
 Asic1ENSMUSG00000023017Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ASIC2 / acid sensing ion channel subunit 2 / Q16515* / Q925H0* / Acid-sensing ion channel 2 *ENSGALG0000000036753
ASIC4 / acid sensing ion channel subunit family member 4 / Q7TNS7* / Q96FT7* / Acid-sensing ion channel 4 *ENSGALG0000001125052
SCNN1B / sodium channel epithelial 1 beta subunit / P51168* / Q9WU38* / sodium channel, nonvoltage-gated 1 beta*ENSGALG0000000620224
SCNN1G / sodium channel epithelial 1 gamma subunit / P51170* / Q9WU39* / Amiloride-sensitive sodium channel subunit gamma *ENSGALG0000000627023
SCNN1A / amiloride-sensitive sodium channel subunit alpha / P37088* / sodium channel, nonvoltage-gated 1 alpha* / sodium channel epithelial 1 alpha subunit*ENSGALG0000004042423
ENSGALG0000001982422
SCNN1D / sodium channel epithelial 1 delta subunit / P51172*ENSGALG0000000183519
ASIC5 / acid sensing ion channel subunit family member 5 / Q9NY37* / Q9R0Y1* / Acid-sensing ion channel 5 *ENSGALG0000000936617


Protein motifs (from Interpro)
Interpro ID Name
 IPR001873  Epithelial sodium channel
 IPR004724  Epithelial sodium channel, chordates
 IPR006109  Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal
 IPR006168  Glycerol-3-phosphate dehydrogenase, NAD-dependent
 IPR008927  6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily
 IPR011128  Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal
 IPR013328  6-phosphogluconate dehydrogenase, domain 2
 IPR016040  NAD(P)-binding domain
 IPR017751  Glycerol-3-phosphate dehydrogenase, NAD-dependent, eukaryotic
 IPR020903  Epithelial sodium channel, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0005975 carbohydrate metabolic process IEA
 biological_processGO:0006072 glycerol-3-phosphate metabolic process IEA
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006812 cation transport IEA
 biological_processGO:0006814 sodium ion transport IEA
 biological_processGO:0007613 memory IEA
 biological_processGO:0008306 associative learning IEA
 biological_processGO:0010447 response to acidic pH IEA
 biological_processGO:0034220 ion transmembrane transport IEA
 biological_processGO:0035725 sodium ion transmembrane transport IDA
 biological_processGO:0042391 regulation of membrane potential IEA
 biological_processGO:0046168 glycerol-3-phosphate catabolic process IEA
 biological_processGO:0046929 negative regulation of neurotransmitter secretion IEA
 biological_processGO:0050915 sensory perception of sour taste IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0070207 protein homotrimerization IDA
 biological_processGO:0070588 calcium ion transmembrane transport IEA
 biological_processGO:0071467 cellular response to pH IDA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0009331 glycerol-3-phosphate dehydrogenase complex IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0045202 synapse IEA
 molecular_functionGO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity IEA
 molecular_functionGO:0005261 cation channel activity IEA
 molecular_functionGO:0005272 sodium channel activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0015280 ligand-gated sodium channel activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEA
 molecular_functionGO:0022839 ion gated channel activity IEA
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0044736 acid-sensing ion channel activity IDA
 molecular_functionGO:0051287 NAD binding IEA


Pathways (from Reactome)
Pathway description
Stimuli-sensing channels


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000017039 STOML3 / stomatin like 3 / Q6PE84* / Q8TAV4* / stomatin (Epb7.2)-like 3*  / complex / reaction
 ENSGALG00000034025 ASIC1 / Q1XA76 / Acid-sensing ion channel 1 / P78348* / Q6NXK8* / acid sensing ion channel subunit 1*  / complex






 

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