ENSGALG00000006488


Gallus gallus

Features
Gene ID: ENSGALG00000006488
  
Biological name :RYK
  
Synonyms : receptor-like tyrosine kinase / RYK
  
Possible biological names infered from orthology : Q01887 / Tyrosine-protein kinase RYK
  
Species: Gallus gallus
  
Chr. number: 9
Strand: 1
Band:
Gene start: 4479194
Gene end: 4530082
  
Corresponding Affymetrix probe sets: Gga.3751.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000010474
NCBI entrez gene - 395409     See in Manteia.
RefSeq - XM_015277134
RefSeq - XM_422674
swissprot - F1NYV9
Ensembl - ENSGALG00000006488
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rykENSDARG00000007231Danio rerio
 RYKENSG00000163785Homo sapiens
 RykENSMUSG00000032547Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MERTK / tyrosine-protein kinase Mer precursor / Q12866* / Q60805* / Tyrosine-protein kinase Mer * / MER proto-oncogene, tyrosine kinase*ENSGALG0000000825726
MST1R / macrophage-stimulating protein receptor precursor / Q04912* / Q62190* / macrophage stimulating 1 receptor* / macrophage stimulating 1 receptor (c-met-related tyrosine kinase)*ENSGALG0000000310325
TYRO3 / tyrosine-protein kinase receptor TYRO3 precursor / Q06418* / P55144* / TYRO3 protein tyrosine kinase* / TYRO3 protein tyrosine kinase 3*ENSGALG0000000863124
MET / hepatocyte growth factor receptor precursor / P08581* / MET proto-oncogene, receptor tyrosine kinase*ENSGALG0000003688324
TIE1 / tyrosine kinase with immunoglobulin like and EGF like domains 1 / P35590* / Q06806*ENSGALG0000000995721
TEK / TEK receptor tyrosine kinase / Q02763* / Q02858*ENSGALG0000000184020


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR001245  Serine-threonine/tyrosine-protein kinase, catalytic domain
 IPR003306  WIF domain
 IPR008266  Tyrosine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007409 axonogenesis IEA
 biological_processGO:0007411 axon guidance IEA
 biological_processGO:0016055 Wnt signaling pathway IEA
 biological_processGO:0022038 corpus callosum development IEA
 biological_processGO:0030182 neuron differentiation IEA
 biological_processGO:0031175 neuron projection development IEA
 biological_processGO:0036518 chemorepulsion of dopaminergic neuron axon IEA
 biological_processGO:0048705 skeletal system morphogenesis IEA
 biological_processGO:0048843 negative regulation of axon extension involved in axon guidance IEA
 biological_processGO:0050919 negative chemotaxis IEA
 biological_processGO:0071679 commissural neuron axon guidance IEA
 biological_processGO:1904938 planar cell polarity pathway involved in axon guidance IEA
 biological_processGO:1904948 midbrain dopaminergic neuron differentiation IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0005109 frizzled binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0017147 Wnt-protein binding IEA
 molecular_functionGO:0042813 Wnt-activated receptor activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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