ENSGALG00000009957


Gallus gallus

Features
Gene ID: ENSGALG00000009957
  
Biological name :TIE1
  
Synonyms : TIE1 / tyrosine kinase with immunoglobulin like and EGF like domains 1
  
Possible biological names infered from orthology : P35590 / Q06806
  
Species: Gallus gallus
  
Chr. number: 8
Strand: 1
Band:
Gene start: 19730043
Gene end: 19741073
  
Corresponding Affymetrix probe sets: Gga.2462.1.S1_at (Chicken Array)   GgaAffx.23084.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000016165
NCBI entrez gene - 424562     See in Manteia.
RefSeq - XM_015291320
RefSeq - XM_422400
swissprot - F1NGV4
Ensembl - ENSGALG00000009957
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tie1ENSDARG00000004105Danio rerio
 TIE1ENSG00000066056Homo sapiens
 Tie1ENSMUSG00000033191Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TEK / TEK receptor tyrosine kinase / Q02763* / Q02858*ENSGALG0000000184046
MERTK / tyrosine-protein kinase Mer precursor / Q12866* / Q60805* / Tyrosine-protein kinase Mer * / MER proto-oncogene, tyrosine kinase*ENSGALG0000000825717
MST1R / macrophage-stimulating protein receptor precursor / Q04912* / Q62190* / macrophage stimulating 1 receptor* / macrophage stimulating 1 receptor (c-met-related tyrosine kinase)*ENSGALG0000000310316
TYRO3 / tyrosine-protein kinase receptor TYRO3 precursor / Q06418* / P55144* / TYRO3 protein tyrosine kinase* / TYRO3 protein tyrosine kinase 3*ENSGALG0000000863116
MET / hepatocyte growth factor receptor precursor / P08581* / MET proto-oncogene, receptor tyrosine kinase*ENSGALG0000003688315
RYK / receptor-like tyrosine kinase / Q01887* / Tyrosine-protein kinase RYK *ENSGALG0000000648811


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR000742  EGF-like domain
 IPR001245  Serine-threonine/tyrosine-protein kinase, catalytic domain
 IPR003599  Immunoglobulin subtype
 IPR003961  Fibronectin type III
 IPR007110  Immunoglobulin-like domain
 IPR008266  Tyrosine-protein kinase, active site
 IPR009030  Growth factor receptor cysteine-rich domain superfamily
 IPR011009  Protein kinase-like domain superfamily
 IPR013032  EGF-like, conserved site
 IPR013783  Immunoglobulin-like fold
 IPR017441  Protein kinase, ATP binding site
 IPR020635  Tyrosine-protein kinase, catalytic domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001568 blood vessel development IEA
 biological_processGO:0001701 in utero embryonic development IEA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0016525 negative regulation of angiogenesis IEA
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation IEA
 biological_processGO:0030336 negative regulation of cell migration IEA
 biological_processGO:0032526 response to retinoic acid IEA
 biological_processGO:0045026 plasma membrane fusion IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004713 protein tyrosine kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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