ENSGALG00000006882


Gallus gallus
activityST8SIA2transferaseglycosylsialyltransferaseprocessn-glycanendosomemembranefamilygangliosidebiosyntheticproteinglycosylationprocessingoligosaccharidemetabolicsialylationearlygolgiapparatusintegralcomponentrecyclingalpha-n-acetylneuraminatealpha--sialyltransferasetransferringgroupssialicacid

Features
Gene ID: ENSGALG00000006882
  
Biological name :ST8SIA2
  
Synonyms : alpha-2,8-sialyltransferase 8B precursor / ST8SIA2
  
Possible biological names infered from orthology : Alpha-2,8-sialyltransferase 8B / O35696 / Q92186 / ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
  
Species: Gallus gallus
  
Chr. number: 10
Strand: 1
Band:
Gene start: 14510826
Gene end: 14534985
  
Corresponding Affymetrix probe sets: Gga.19493.2.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000052307
Ensembl peptide - ENSGALP00000011134
NCBI entrez gene - 414336     See in Manteia.
RefSeq - XM_015292082
RefSeq - NM_001001604
RefSeq Peptide - NP_001001604
swissprot - A0A1D5PHM7
swissprot - F1NIM6
Ensembl - ENSGALG00000006882
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 st8sia2ENSDARG00000018788Danio rerio
 Q92186ENSG00000140557Homo sapiens
 O35696ENSMUSG00000025789Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ST8SIA4 / CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase / Q64692* / Q92187* / ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4*ENSGALG0000002619257
ST8SIA3Z / O43173* / Q64689* / ST8SIA3* / ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3* / Sia-alpha-2,3-Gal-beta-1,4-GlcNAc-R:alpha 2,8-sialyltransferase *ENSGALG0000003915132
O43173* / Q64689* / ST8SIA3* / ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3* / Sia-alpha-2,3-Gal-beta-1,4-GlcNAc-R:alpha 2,8-sialyltransferase *ENSGALG0000002699131
ST8SIA5 / ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 / O15466* / P70126* / Alpha-2,8-sialyltransferase 8E *ENSGALG0000003592727
ST8SIA1 / ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 / Q64687* / Q92185* / Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase *ENSGALG0000001321126
ST8SIA6 / alpha-2,8-sialyltransferase 8F / P61647* / Q8K4T1* / ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6*ENSGALG0000000867125


Protein motifs (from Interpro)
Interpro ID Name
 IPR001675  Glycosyl transferase family 29
 IPR012163  Sialyltransferase


Gene Ontology (GO)
nitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processglycosylationnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processglycosylationnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processglycosylationnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processglycosylationnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processglycosylationnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processglycosylationnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processglycosylationnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processglycosylationnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processglycosylationnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processglycosylationnitrogen compound metabnitrogen compound metabolic processbiosynthetic processbiosynthetic processcellular metabolic proccellular metabolic processprimary metabolic proceprimary metabolic processorganic substance metaborganic substance metabolic processglycosylationglycosylation
transferase activitytransferase activitytransferase activitytransferase activitytransferase activitytransferase activitytransferase activitytransferase activitytransferase activitytransferase activitytransferase activitytransferase activity
cellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellcellorganelleorganellemembranemembrane
TypeGO IDTermEv.Code
 biological_processGO:0001574 ganglioside biosynthetic process IEA
 biological_processGO:0006486 protein glycosylation IEA
 biological_processGO:0006491 N-glycan processing IEA
 biological_processGO:0009311 oligosaccharide metabolic process IEA
 biological_processGO:0097503 sialylation IEA
 cellular_componentGO:0005769 early endosome IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0055037 recycling endosome IEA
 molecular_functionGO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity IEA
 molecular_functionGO:0008373 sialyltransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016757 transferase activity, transferring glycosyl groups IEA


Pathways (from Reactome)
Pathway description
Sialic acid metabolism
NCAM1 interactions
N-Glycan antennae elongation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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