| MP:0000780 | abnormal corpus callosum morphology | "malformation or absence of a thick bundle of nerve fibers comprising a commissural plate connecting the two cerebral hemispheres; it consists of contralateral axon projections that provides communications between the right and left cerebral hemispheres" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Kiss1rtm1Rla/Kiss1rtm1Rla
Genetic Background: involves: 129S1/SvImJ
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| MP:0000788 | abnormal cerebral cortex morphology | "malformed gray cellular mantle covering the surface of the brain" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:38857] |
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Allelic Composition: Kiss1rtm1Rla/Kiss1rtm1Rla
Genetic Background: involves: 129S1/SvImJ
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| MP:0000807 | abnormal hippocampus morphology | "absent or malformed deep lying structure of the cerebrum involved with memory storage and spatial navigation" [The Atlas of Mouse Development:ISBN 0-12-402035-6, MGI:Cls, J:38857] |
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Allelic Composition: Cux1tm1Mbu/Cux1tm1Mbu
Genetic Background: involves: OF1
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| MP:0000823 | abnormal lateral ventricle morphology | "malformation or absence of cavity in each of the cerebral hemispheres derived from the cavity of the embryonic neural tube; they are separated from each other by the septum pellucidum, and each communicates with the third ventricle by the foramen of Monro, through which also the choroid plexuses of the lateral ventricles become continuous with that of the third ventricle" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Kiss1rtm1Rla/Kiss1rtm1Rla
Genetic Background: involves: 129S1/SvImJ
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| MP:0000825 | dilated lateral ventricles | "increase over the normal size of the horseshoe-shaped cavities of the cerebrum" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:38857] |
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Allelic Composition: Kiss1rtm1Rla/Kiss1rtm1Rla
Genetic Background: involves: 129S1/SvImJ
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| MP:0000830 | abnormal diencephalon morphology | "any malformation or absence of the paired caudal parts of the prosencephalon from which the thalamus, hypothalamus, epithalamus and subthalamus are derived; these regions regulate autonomic, visceral and endocrine function, and process information directed to the cerebral cortex" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3] |
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Allelic Composition: Kiss1rtm1Rla/Kiss1rtm1Rla
Genetic Background: involves: 129S1/SvImJ
|
| MP:0000852 | small cerebellum | "reduced size of cerebellum" [MGI:CLS, J:17203, J:67524] |
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Allelic Composition: Kiss1rtm1Rla/Kiss1rtm1Rla
Genetic Background: involves: 129S1/SvImJ
|
| MP:0000952 | abnormal CNS glia | "anomalous structure, number or composition of non-neuronal cells of the central nervous system that form the myelin insulation of nervous pathways, guide neuronal migration during development, and exchange metabolites with neurons" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Kiss1rtm1Rla/Kiss1rtm1Rla
Genetic Background: involves: 129S1/SvImJ
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| MP:0001265 | reduced body size | "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170] |
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Allelic Composition: Kiss1rtm1Rla/Kiss1rtm1Rla
Genetic Background: involves: 129S1/SvImJ
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| MP:0001415 | increased exploration in new environment | "greater amount of time spent investigating new location" [J:28825] |
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Allelic Composition: Cux1tm1Mbu/Cux1tm1Mbu
Genetic Background: involves: OF1
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| MP:0001454 | abnormal cued conditioning behavior | "defect in the ability of an animal to learn and remember an association between an an aversive experience (the unconditioned stimulus (US), ususally a shock) and a neutral stimulus (the conditioned stimulus (CS), usually an auditory cue or light)" [CFG:Center for Functional Genomics , Northwestern University] |
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Allelic Composition: Cux1tm1Mbu/Cux1tm1Mbu
Genetic Background: involves: OF1
|
| MP:0001469 | abnormal contextual conditioning | "defect in the ability of an animal to learn and remember an association between an an aversive experience (the unconditioned stimulus (US), ususally a shock) and a neutral stimulus (the conditioned stimulus (CS), or the environmental context in this case)" [CFG:Center for Functional Genomics , Northwestern University] |
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Allelic Composition: Cux1tm1Mbu/Cux1tm1Mbu
Genetic Background: involves: OF1
|
| MP:0002066 | abnormal motor capabilities/coordination/movement | "altered ability to coordinate voluntary movement or repetitive, compulsive movements" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Kiss1rtm1Rla/Kiss1rtm1Rla
Genetic Background: involves: 129S1/SvImJ
|
| MP:0002152 | abnormal brain morphology | "anomalous structure of or abnormal development of the brain, one of the two components of the central nervous system and the center of thought and emotion; controls coordination, bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.)" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, http://cancerweb.ncl.ac.uk] |
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Allelic Composition: Kiss1rtm1Rla/Kiss1rtm1Rla
Genetic Background: involves: 129S1/SvImJ
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| MP:0002182 | abnormal astrocyte morphology | "anomalous structure, number or compostion of one of the large neuroglia cells of nervous tissue" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Kiss1rtm1Rla/Kiss1rtm1Rla
Genetic Background: involves: 129S1/SvImJ
|
| MP:0002741 | small olfactory bulb | "reduced size of the forebrain region that coordinates neuronal signaling involved in the perception of smell; it receives input from the sensory neurons and outputs to the olfactory cortex" [J:79871] |
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Allelic Composition: Kiss1rtm1Rla/Kiss1rtm1Rla
Genetic Background: involves: 129S1/SvImJ
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| MP:0002761 | abnormal hippocampal mossy fiber morphology | "absence or misprojection of axons of neuronal cells in the dentate gyrus" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, J:4978] |
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Allelic Composition: Cux1tm1Mbu/Cux1tm1Mbu
Genetic Background: involves: OF1
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| MP:0002799 | abnormal passive avoidance behavior | "defects in the ability of an animal to enter an hostile environment where it receives a unpleasant or punishing stimuli applied previously with prolonged latency" [CFG:Center for Functional Genomics , Northwestern University] |
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Allelic Composition: Cux1tm1Mbu/Cux1tm1Mbu
Genetic Background: involves: OF1
|
| MP:0003203 | increased neuron apoptosis | "increase in the number of neurons undergoing programmed cell death" [RGD:Rat Genome Database submission] |
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Allelic Composition: Kiss1rtm1Rla/Kiss1rtm1Rla
Genetic Background: involves: 129S1/SvImJ
|
| MP:0003240 | loss of hippocampal neurons | "loss of neurons in the hippocampal region of the brain, commonly due to an apoptotic event" [RGD:Rat Genome Database submission] |
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Allelic Composition: Kiss1rtm1Rla/Kiss1rtm1Rla
Genetic Background: involves: 129S1/SvImJ
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| MP:0004101 | abnormal brain interneuron morphology | "malformation or absence of neurons that exclusively interact with other neurons in the brain; this includes most brain neuronal cell types" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Kiss1rtm1Rla/Kiss1rtm1Rla
Genetic Background: involves: 129S1/SvImJ
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| MP:0004275 | abnormal postnatal subventricular zone morphology | "any structural anomaly of the mitotically active layer of cells surrounding the brain ventricles in the adult that consists of migrating neuroblasts, astrocytes and transitory amplifying progenitor cells" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", PMID:12637172] |
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Allelic Composition: Kiss1rtm1Rla/Kiss1rtm1Rla
Genetic Background: involves: 129S1/SvImJ
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| MP:0004279 | abnormal rostral migratory stream morphology | "any structural anomaly of the transient structure formed by neurons migrating from the subventricular zone into the olfactory bulbs" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Kiss1rtm1Rla/Kiss1rtm1Rla
Genetic Background: involves: 129S1/SvImJ
|
| MP:0006009 | abnormal neuronal migration | "defective or impaired movement of immature neurons from germinal zones to specific positions where they will reside as they mature" [smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Kiss1rtm1Rla/Kiss1rtm1Rla
Genetic Background: involves: 129S1/SvImJ
|
| MP:0006254 | thin cerebral cortex | "decreased depth of the mantle covering the surface of the cerebral hemispheres" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:84683] |
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Allelic Composition: Kiss1rtm1Rla/Kiss1rtm1Rla
Genetic Background: involves: 129S1/SvImJ
|
| MP:0009937 | abnormal neuron differentiation | "abnormal growth or development of the cells of the nervous system that receive, conduct, and transmit impulses" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Kiss1rtm1Rla/Kiss1rtm1Rla
Genetic Background: involves: 129S1/SvImJ
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| MP:0009969 | abnormal cerebral cortex pyramidal cell morphology | "any structural anomaly of the projection neurons in the pyramidal cell layer of the cerebral cortex" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Kiss1rtm1Rla/Kiss1rtm1Rla
Genetic Background: involves: 129S1/SvImJ
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| MP:0009974 | decreased cerebral cortex pyramidal cell number | "reduced number of the projection neurons in the pyramidal cell layer of the cerebral cortex" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Kiss1rtm1Rla/Kiss1rtm1Rla
Genetic Background: involves: 129S1/SvImJ
Allelic Composition: St8sia2tm1Jxm/St8sia2tm1Jxm,St8sia4tm1.1Mifu/St8sia4tm1.1Mifu,Tg(Thy1-YFP)HJrs/?
Genetic Background: involves: C57BL/6 * CBA
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| MP:0010012 | ectopic cerebral cortex pyramidal cells | "the cerebral cortex pyramidal cell body resides in places other than the pyramidal cell layer of the cerebral cortex" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Kiss1rtm1Rla/Kiss1rtm1Rla
Genetic Background: involves: 129S1/SvImJ
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| MP:0011085 | complete postnatal lethality | "premature death anytime between the neonatal period and weaning age of all organisms of a given genotype in a population (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith] |
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Allelic Composition: Kiss1rtm1Rla/Kiss1rtm1Rla
Genetic Background: involves: 129S1/SvImJ
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| MP:0012468 | decreased striatum area | "reduced size of a large cluster of dopaminergic nerve cells, consisting of the caudate nucleus and the putamen, that controls movement, balance, and walking" [ISBN:0838580343, MGI:csmith] |
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Allelic Composition: Kiss1rtm1Rla/Kiss1rtm1Rla
Genetic Background: involves: 129S1/SvImJ
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