ENSGALG00000007511


Gallus gallus

Features
Gene ID: ENSGALG00000007511
  
Biological name :ITGB2
  
Synonyms : integrin beta-2 precursor / ITGB2
  
Possible biological names infered from orthology : Integrin beta-2-like protein / integrin subunit beta 2 / Itgb2l / P05107 / Q3UV74
  
Species: Gallus gallus
  
Chr. number: 7
Strand: -1
Band:
Gene start: 7169891
Gene end: 7181477
  
Corresponding Affymetrix probe sets: Gga.4507.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000012130
NCBI entrez gene - 396181     See in Manteia.
RefSeq - XM_015289136
RefSeq - NM_205251
RefSeq - XM_015289134
RefSeq - XM_015289135
RefSeq Peptide - NP_990582
swissprot - F1NM67
Ensembl - ENSGALG00000007511
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 itgb2ENSDARG00000016939Danio rerio
 ITGB2ENSG00000160255Homo sapiens
 Itgb2ENSMUSG00000000290Mus musculus
 Itgb2lENSMUSG00000000157Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ITGB1 / integrin subunit beta 1 / P05556* / P09055* / Integrin beta-1 *ENSGALG0000000714548
ITGB5 / integrin beta-5 precursor / P18084* / integrin subunit beta 5*ENSGALG0000002976640
ITGB6 / integrin subunit beta 6 / P18564* / Q9Z0T9* / Integrin beta-6 *ENSGALG0000001114139
ITGB3 / P05106* / O54890* / AC068234.1* / Integrin beta-3 * / integrin subunit beta 3*ENSGALG0000000037938
ITGB4 / integrin subunit beta 4 / A2A863* / P16144* / Integrin beta-4 *ENSGALG0000000238934
ITGB8 / integrin subunit beta 8 / P26012*ENSGALG0000001087530
ITGBL1 / integrin subunit beta like 1 / O95965* / Q8VDV0* / Integrin beta-like protein 1 *ENSGALG0000001686714


Protein motifs (from Interpro)
Interpro ID Name
 IPR002035  von Willebrand factor, type A
 IPR002369  Integrin beta subunit, VWA domain
 IPR012896  Integrin beta subunit, tail
 IPR014836  Integrin beta subunit, cytoplasmic domain
 IPR015439  Integrin beta-2 subunit
 IPR015812  Integrin beta subunit
 IPR016201  PSI domain
 IPR032695  Integrin domain superfamily
 IPR033760  Integrin beta N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007159 leukocyte cell-cell adhesion IEA
 biological_processGO:0007160 cell-matrix adhesion IEA
 biological_processGO:0007229 integrin-mediated signaling pathway IEA
 biological_processGO:0030593 neutrophil chemotaxis IEA
 biological_processGO:0032930 positive regulation of superoxide anion generation IEA
 biological_processGO:0034113 heterotypic cell-cell adhesion IEA
 biological_processGO:0035987 endodermal cell differentiation IEA
 biological_processGO:0043113 receptor clustering IEA
 biological_processGO:0043315 positive regulation of neutrophil degranulation IEA
 biological_processGO:0050730 regulation of peptidyl-tyrosine phosphorylation IEA
 biological_processGO:1990266 neutrophil migration IEA
 cellular_componentGO:0008305 integrin complex IEA
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0034687 integrin alphaL-beta2 complex IEA
 cellular_componentGO:0043235 receptor complex IEA
 cellular_componentGO:0044853 plasma membrane raft IEA
 cellular_componentGO:0099568 cytoplasmic region IEA
 molecular_functionGO:0019901 protein kinase binding IEA
 molecular_functionGO:0030369 ICAM-3 receptor activity IEA
 molecular_functionGO:0031072 heat shock protein binding IEA
 molecular_functionGO:0050839 cell adhesion molecule binding IEA


Pathways (from Reactome)
Pathway description
Toll Like Receptor 4 (TLR4) Cascade
Cell surface interactions at the vascular wall
Integrin cell surface interactions
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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