ENSGALG00000007948


Gallus gallus
repeatLRRC4Csubtypeimmunoglobulinproteinregulationimmunoglobulin-likedomainkinaseactivitymembranecysteine-richflankingregionc-terminaltypicali-setfoldrepeat-containingcleucinerichsuperfamilycytokine-mediatedsignalingpathwayjak-statcascadeaxonogenesiscytoplasm

Features
Gene ID: ENSGALG00000007948
  
Biological name :LRRC4C
  
Synonyms : leucine rich repeat containing 4C / LRRC4C
  
Possible biological names infered from orthology : Leucine-rich repeat-containing protein 4C / Q8C031 / Q9HCJ2
  
Species: Gallus gallus
  
Chr. number: 5
Strand: -1
Band:
Gene start: 20507334
Gene end: 20509250
  
Corresponding Affymetrix probe sets: GgaAffx.4980.1.A1_at (Chicken Array)   GgaAffx.4980.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000012895
NCBI entrez gene - 428862     See in Manteia.
RefSeq - XM_004941552
RefSeq - XM_015287200
RefSeq - XM_015287201
RefSeq - XM_015287202
RefSeq - XM_015287203
RefSeq - XM_015287204
RefSeq - XM_015287205
RefSeq - XM_015287206
RefSeq - XM_015287207
RefSeq - XM_004941551
swissprot - F1NTY3
Ensembl - ENSGALG00000007948
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lrrc4cENSDARG00000113411Danio rerio
 si:dkey-6l15.1ENSDARG00000016739Danio rerio
 LRRC4CENSG00000148948Homo sapiens
 Lrrc4cENSMUSG00000050587Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
LINGO2 / leucine rich repeat and Ig domain containing 2 / Q3URE9* / Q7L985*ENSGALG0000000186925
LINGO1 / Q50L44 / Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 / Q9D1T0* / Q96FE5* / leucine rich repeat and Ig domain containing 1*ENSGALG0000000270825
LINGO3 / leucine rich repeat and Ig domain containing 3 / P0C6S8* / Q6GQU6* / Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 3 *ENSGALG0000000080624
LRFN5 / leucine rich repeat and fibronectin type III domain containing 5 / Q8BXA0* / Q96NI6* / Leucine-rich repeat and fibronectin type-III domain-containing protein 5 *ENSGALG0000001250522
LRRN1 / leucine rich repeat neuronal 1 / Q61809* / Q6UXK5* / Leucine-rich repeat neuronal protein 1 *ENSGALG0000003509922
LRRN2 / leucine rich repeat neuronal 2 / O75325* / leucine rich repeat protein 2, neuronal*ENSGALG0000000063921
LRRN3 / leucine rich repeat neuronal 3 / Q8CBC6* / Q9H3W5* / Leucine-rich repeat neuronal protein 3 *ENSGALG0000000948821
LRFN2 / leucine rich repeat and fibronectin type III domain containing 2 / Q80TG9* / Q9ULH4* / Leucine-rich repeat and fibronectin type-III domain-containing protein 2 *ENSGALG0000001005018


Protein motifs (from Interpro)
Interpro ID Name
 IPR000483  Cysteine-rich flanking region, C-terminal
 IPR001611  Leucine-rich repeat
 IPR003591  Leucine-rich repeat, typical subtype
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR013098  Immunoglobulin I-set
 IPR013783  Immunoglobulin-like fold
 IPR026878  Leucine-rich repeat-containing protein 4C
 IPR026906  Leucine rich repeat 5
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
nitrogen compound metabolic processcellular metabolic processprimary metabolic processregulation of molecular functionorganic substance metabolic processcell communicationresponse to chemicalcellular response to stimuluscellular component organizationanatomical structure developmentcellular developmental processnitrogen compound metabolic processcellular metabolic processprimary metabolic processregulation of molecular functionorganic substance metabolic processcell communicationresponse to chemicalcellular response to stimuluscellular component organizationanatomical structure developmentcellular developmental processnitrogen compound metabolic processcellular metabolic processprimary metabolic processregulation of molecular functionorganic substance metabolic processcell communicationresponse to chemicalcellular response to stimuluscellular component organizationanatomical structure developmentcellular developmental processnitrogen compound metabolic processcellular metabolic processprimary metabolic processregulation of molecular functionorganic substance metabolic processcell communicationresponse to chemicalcellular response to stimuluscellular component organizationanatomical structure developmentcellular developmental processnitrogen compound metabolic processcellular metabolic processprimary metabolic processregulation of molecular functionorganic substance metabolic processcell communicationresponse to chemicalcellular response to stimuluscellular component organizationanatomical structure developmentcellular developmental processnitrogen compound metabolic processcellular metabolic processprimary metabolic processregulation of molecular functionorganic substance metabolic processcell communicationresponse to chemicalcellular response to stimuluscellular component organizationanatomical structure developmentcellular developmental processnitrogen compound metabolic processcellular metabolic processprimary metabolic processregulation of molecular functionorganic substance metabolic processcell communicationresponse to chemicalcellular response to stimuluscellular component organizationanatomical structure developmentcellular developmental processnitrogen compound metabolic processcellular metabolic processprimary metabolic processregulation of molecular functionorganic substance metabolic processcell communicationresponse to chemicalcellular response to stimuluscellular component organizationanatomical structure developmentcellular developmental processnitrogen compound metabolic processcellular metabolic processprimary metabolic processregulation of molecular functionorganic substance metabolic processcell communicationresponse to chemicalcellular response to stimuluscellular component organizationanatomical structure developmentcellular developmental processnitrogen compound metabolic processcellular metabolic processprimary metabolic processregulation of molecular functionorganic substance metabolic processcell communicationresponse to chemicalcellular response to stimuluscellular component organizationanatomical structure developmentcellular developmental processnitrogen comnitrogen compound metabolic processcellular metcellular metabolic processprimary metaprimary metabolic processregulation oregulation of molecular functionorganic subsorganic substance metabolic processcell communicell communicationresponse to response to chemicalcellular rescellular response to stimuluscellular comcellular component organizationanatomical sanatomical structure developmentcellular devcellular developmental process
enzyme regulator activityenzyme regulator activityenzyme regulator activityenzyme regulator activityenzyme regulator activityenzyme regulator activityenzyme regulator activityenzyme regulator activityenzyme regulator activityenzyme regulator activityenzyme regulator activityenzyme regulator activity
cellmembranecellmembranecellmembranecellmembranecellmembranecellmembranecellmembranecellmembranecellmembranecellmembranecellcellmembranemembrane
TypeGO IDTermEv.Code
 biological_processGO:0006469 negative regulation of protein kinase activity IBA
 biological_processGO:0019221 cytokine-mediated signaling pathway IBA
 biological_processGO:0046426 negative regulation of JAK-STAT cascade IBA
 biological_processGO:0050770 regulation of axonogenesis IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004860 protein kinase inhibitor activity IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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