ENSGALG00000010448


Gallus gallus

Features
Gene ID: ENSGALG00000010448
  
Biological name :LTBP1
  
Synonyms : latent-transforming growth factor beta-binding protein 1 precursor / LTBP1
  
Possible biological names infered from orthology : latent transforming growth factor beta binding protein 1 / Q14766 / Q8CG19
  
Species: Gallus gallus
  
Chr. number: 3
Strand: -1
Band:
Gene start: 31210825
Gene end: 31393401
  
Corresponding Affymetrix probe sets: Gga.2535.1.S1_at (Chicken Array)   Gga.2535.2.S1_a_at (Chicken Array)   GgaAffx.23234.2.S1_s_at (Chicken Array)   GgaAffx.23234.3.S1_at (Chicken Array)   GgaAffx.6607.1.S1_at (Chicken Array)   GgaAffx.6607.2.S1_s_at (Chicken Array)   GgaAffx.6656.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000060062
Ensembl peptide - ENSGALP00000016993
NCBI entrez gene - 421461     See in Manteia.
RefSeq - XM_015283725
RefSeq - XM_015283722
RefSeq - XM_015283723
RefSeq - XM_015283724
RefSeq - NM_001282608
RefSeq - XM_003640980
RefSeq - XM_015283720
RefSeq - XM_015283721
RefSeq Peptide - NP_001269537
swissprot - F1N9I4
swissprot - A0A1L1RMS9
Ensembl - ENSGALG00000010448
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ltbp1ENSDARG00000056922Danio rerio
 LTBP1ENSG00000049323Homo sapiens
 Ltbp1ENSMUSG00000001870Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
LTBP2 / latent transforming growth factor beta binding protein 2 / Q14767*ENSGALG0000001025839
FBN1 / fibrillin 1 / P35555* / Q61554* / Fibrillin-1 Asprosin*ENSGALG0000000496026
ENSGALG0000003762526
FBN2 / fibrillin 2 / P35556* / Q61555* / Fibrillin-2 Fibrillin-2 C-terminal peptide*ENSGALG0000001468624
FBLN1 / fibulin-1 precursor / P23142* / Q08879* / fibulin 1* / Mus musculus fibulin 1 (Fbln1), transcript variant 2, mRNA.*ENSGALG0000001423311
ENSGALG000000377117
ENSGALG000000051206
FBLN5 / fibulin 5 / Q9UBX5* / Q9WVH9*ENSGALG000000107476
EFEMP1 / EGF containing fibulin extracellular matrix protein 1 / Q12805* / Q8BPB5* / EGF-containing fibulin-like extracellular matrix protein 1 *ENSGALG000000379016


Protein motifs (from Interpro)
Interpro ID Name
 IPR000152  EGF-type aspartate/asparagine hydroxylation site
 IPR000742  EGF-like domain
 IPR001881  EGF-like calcium-binding domain
 IPR009030  Growth factor receptor cysteine-rich domain superfamily
 IPR013032  EGF-like, conserved site
 IPR017878  TB domain
 IPR018097  EGF-like calcium-binding, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003281 ventricular septum development IEA
 biological_processGO:0035904 aorta development IEA
 biological_processGO:0060976 coronary vasculature development IEA
 cellular_componentGO:0001527 microfibril IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0031012 extracellular matrix IEA
 cellular_componentGO:0032991 protein-containing complex IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0050431 transforming growth factor beta binding IEA
 molecular_functionGO:0050436 microfibril binding IEA


Pathways (from Reactome)
Pathway description
Molecules associated with elastic fibres
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Post-translational protein phosphorylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000009612 TGFB2 / P27090* / P61812* / transforming growth factor beta 2* / Transforming growth factor beta-2 Latency-associated peptide*  / complex / reaction
 ENSGALG00000010346 TGFB3 / transforming growth factor beta 3 / P10600*  / complex / reaction






 

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