ENSGALG00000010909


Gallus gallus

Features
Gene ID: ENSGALG00000010909
  
Biological name :PRKG2
  
Synonyms : PRKG2 / protein kinase, cGMP-dependent, type II
  
Possible biological names infered from orthology : Q13237
  
Species: Gallus gallus
  
Chr. number: 4
Strand: 1
Band:
Gene start: 45935473
Gene end: 45954816
  
Corresponding Affymetrix probe sets: GgaAffx.6904.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000017721
NCBI entrez gene - 428753     See in Manteia.
RefSeq - XM_004941095
RefSeq - XM_004941096
RefSeq - XM_015276512
RefSeq - XM_015276513
RefSeq - XM_003641188
swissprot - E1C4W9
Ensembl - ENSGALG00000010909
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 prkg2ENSDARG00000054741Danio rerio
 PRKG2ENSG00000138669Homo sapiens
 Prkg2ENSMUSG00000029334Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PRKG1 / protein kinase, cGMP-dependent, type I / P0C605* / Q13976*ENSGALG0000000380545
ENSGALG0000004254329
PRKACB / protein kinase cAMP-activated catalytic subunit beta / P22694* / P68181* / protein kinase, cAMP dependent, catalytic, beta*ENSGALG0000002853020
PRKX / protein kinase, X-linked / P51817* / Q922R0* / cAMP-dependent protein kinase catalytic subunit PRKX *ENSGALG0000004275919


Protein motifs (from Interpro)
Interpro ID Name
 IPR000595  Cyclic nucleotide-binding domain
 IPR000719  Protein kinase domain
 IPR000961  AGC-kinase, C-terminal
 IPR002374  cGMP-dependent kinase
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR014710  RmlC-like jelly roll fold
 IPR017441  Protein kinase, ATP binding site
 IPR018488  Cyclic nucleotide-binding, conserved site
 IPR018490  Cyclic nucleotide-binding-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0016310 phosphorylation IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0004692 cGMP-dependent protein kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0030553 cGMP binding IEA


Pathways (from Reactome)
Pathway description
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
cGMP effects


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000000067 SPR / sepiapterin reductase / P35270*  / reaction
 ENSGALG00000008294 ITPR1 / inositol 1,4,5-trisphosphate receptor type 1 / P11881* / Q14643*  / reaction
 ENSGALG00000007848 PTS / 6-pyruvoyltetrahydropterin synthase / Q03393* / Q9R1Z7* / 6-pyruvoyl-tetrahydropterin synthase*  / reaction






 

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