ENSGALG00000011811


Gallus gallus
nuclearSYNE2membranemigrationdomaincellspectrinenveloperegulationlocalizationnucleusfilamentactinbindingactinin-typeactin-bindingconservedsitecalponinhomologyrepeatkashalpha-actininnesprin-organizationestablishmentmaintenancepolarityfibroblastnucleokinesisinvolved

Features
Gene ID: ENSGALG00000011811
  
Biological name :SYNE2
  
Synonyms : spectrin repeat containing nuclear envelope protein 2 / SYNE2
  
Possible biological names infered from orthology : Q6ZWQ0 / Q8WXH0 / spectrin repeat containing, nuclear envelope 2
  
Species: Gallus gallus
  
Chr. number: 5
Strand: -1
Band:
Gene start: 53126301
Gene end: 53282964
  
Corresponding Affymetrix probe sets: Gga.15111.1.S1_s_at (Chicken Array)   Gga.17077.1.S1_s_at (Chicken Array)   Gga.17898.1.A1_at (Chicken Array)   Gga.17898.1.S1_s_at (Chicken Array)   Gga.2524.1.S1_at (Chicken Array)   GgaAffx.23677.2.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000019252
Ensembl peptide - ENSGALP00000046942
NCBI entrez gene - 423509     See in Manteia.
RefSeq - XM_015287888
RefSeq - XM_015287886
RefSeq - XM_015287887
RefSeq - XM_015287882
RefSeq - XM_015287883
RefSeq - XM_015287884
RefSeq - XM_015287885
swissprot - E1BZI5
swissprot - A0A1D5P2P4
Ensembl - ENSGALG00000011811
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:ch211-207i1.2ENSDARG00000030107Danio rerio
 syne2bENSDARG00000053484Danio rerio
 SYNE2ENSG00000054654Homo sapiens
 Syne2ENSMUSG00000063450Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SYNE1* / Q6ZWR6* / Q8NF91* / spectrin repeat containing nuclear envelope protein 1* / Mus musculus spectrin repeat containing, nuclear envelope 1 (Syne1), transcript variant 5, mRNA.*ENSGALG0000001350525
FLNB / filamin-B / O75369* / Q80X90*ENSGALG000000056785
SYNE1* / Q6ZWR6* / Q8NF91* / spectrin repeat containing nuclear envelope protein 1* / Mus musculus spectrin repeat containing, nuclear envelope 1 (Syne1), transcript variant 5, mRNA.*ENSGALG000000426385
CLMN / calmin / Q8C5W0* / Q96JQ2*ENSGALG000000307192


Protein motifs (from Interpro)
Interpro ID Name
 IPR001589  Actinin-type actin-binding domain, conserved site
 IPR001715  Calponin homology domain
 IPR002017  Spectrin repeat
 IPR012315  KASH domain
 IPR018159  Spectrin/alpha-actinin
 IPR030266  Nesprin-2


Gene Ontology (GO)
cellular component organizationestablishment of localizationcellular localizationestablishment or maintenance of cell polaritylocalization of cellmovement of cell or subcellular componentanatomical structure developmentcellular developmental processmicrotubule-based processactin filament-based processmacromolecule localizationmicrotubule organizing center localizationregulation of biological qualitycellular component biogenesiscellular component organizationestablishment of localizationcellular localizationestablishment or maintenance of cell polaritylocalization of cellmovement of cell or subcellular componentanatomical structure developmentcellular developmental processmicrotubule-based processactin filament-based processmacromolecule localizationmicrotubule organizing center localizationregulation of biological qualitycellular component biogenesiscellular component organizationestablishment of localizationcellular localizationestablishment or maintenance of cell polaritylocalization of cellmovement of cell or subcellular componentanatomical structure developmentcellular developmental processmicrotubule-based processactin filament-based processmacromolecule localizationmicrotubule organizing center localizationregulation of biological qualitycellular component biogenesiscellular component organizationestablishment of localizationcellular localizationestablishment or maintenance of cell polaritylocalization of cellmovement of cell or subcellular componentanatomical structure developmentcellular developmental processmicrotubule-based processactin filament-based processmacromolecule localizationmicrotubule organizing center localizationregulation of biological qualitycellular component biogenesiscellular component organizationestablishment of localizationcellular localizationestablishment or maintenance of cell polaritylocalization of cellmovement of cell or subcellular componentanatomical structure developmentcellular developmental processmicrotubule-based processactin filament-based processmacromolecule localizationmicrotubule organizing center localizationregulation of biological qualitycellular component biogenesiscellular component organizationestablishment of localizationcellular localizationestablishment or maintenance of cell polaritylocalization of cellmovement of cell or subcellular componentanatomical structure developmentcellular developmental processmicrotubule-based processactin filament-based processmacromolecule localizationmicrotubule organizing center localizationregulation of biological qualitycellular component biogenesiscellular component organizationestablishment of localizationcellular localizationestablishment or maintenance of cell polaritylocalization of cellmovement of cell or subcellular componentanatomical structure developmentcellular developmental processmicrotubule-based processactin filament-based processmacromolecule localizationmicrotubule organizing center localizationregulation of biological qualitycellular component biogenesiscellular component organizationestablishment of localizationcellular localizationestablishment or maintenance of cell polaritylocalization of cellmovement of cell or subcellular componentanatomical structure developmentcellular developmental processmicrotubule-based processactin filament-based processmacromolecule localizationmicrotubule organizing center localizationregulation of biological qualitycellular component biogenesiscellular component organizationestablishment of localizationcellular localizationestablishment or maintenance of cell polaritylocalization of cellmovement of cell or subcellular componentanatomical structure developmentcellular developmental processmicrotubule-based processactin filament-based processmacromolecule localizationmicrotubule organizing center localizationregulation of biological qualitycellular component biogenesiscellular component organizationestablishment of localizationcellular localizationestablishment or maintenance of cell polaritylocalization of cellmovement of cell or subcellular componentanatomical structure developmentcellular developmental processmicrotubule-based processactin filament-based processmacromolecule localizationmicrotubule organizing center localizationregulation of biological qualitycellular component biogenesiscellular ccellular component organizationestablishmestablishment of localizationcellular lcellular localizationestablishmestablishment or maintenance of cell polaritylocalizatilocalization of cellmovement omovement of cell or subcellular componentanatomicalanatomical structure developmentcellular dcellular developmental processmicrotubulmicrotubule-based processactin filaactin filament-based processmacromolecmacromolecule localizationmicrotubulmicrotubule organizing center localizationregulationregulation of biological qualitycellular ccellular component biogenesis
protein bindingprotein-containing complex bindingprotein bindingprotein-containing complex bindingprotein bindingprotein-containing complex bindingprotein bindingprotein-containing complex bindingprotein bindingprotein-containing complex bindingprotein bindingprotein-containing complex bindingprotein bindingprotein-containing complex bindingprotein bindingprotein-containing complex bindingprotein bindingprotein-containing complex bindingprotein bindingprotein-containing complex bindingprotein bindingprotein bindingprotein-containing complex bindingprotein-containing complex binding
cellorganellecell junctionmembranesupramolecular complexmembrane-enclosed lumenprotein-containing complexcellorganellecell junctionmembranesupramolecular complexmembrane-enclosed lumenprotein-containing complexcellorganellecell junctionmembranesupramolecular complexmembrane-enclosed lumenprotein-containing complexcellorganellecell junctionmembranesupramolecular complexmembrane-enclosed lumenprotein-containing complexcellorganellecell junctionmembranesupramolecular complexmembrane-enclosed lumenprotein-containing complexcellorganellecell junctionmembranesupramolecular complexmembrane-enclosed lumenprotein-containing complexcellorganellecell junctionmembranesupramolecular complexmembrane-enclosed lumenprotein-containing complexcellorganellecell junctionmembranesupramolecular complexmembrane-enclosed lumenprotein-containing complexcellorganellecell junctionmembranesupramolecular complexmembrane-enclosed lumenprotein-containing complexcellorganellecell junctionmembranesupramolecular complexmembrane-enclosed lumenprotein-containing complexcellcellorganelleorganellecell junctioncell junctionmembranemembranesupramolecular complsupramolecular complexmembrane-enclosed lumembrane-enclosed lumenprotein-containing cprotein-containing complex
TypeGO IDTermEv.Code
 biological_processGO:0006998 nuclear envelope organization IEA
 biological_processGO:0007097 nuclear migration IEA
 biological_processGO:0007163 establishment or maintenance of cell polarity IEA
 biological_processGO:0010761 fibroblast migration IEA
 biological_processGO:0021817 nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration IEA
 biological_processGO:0030335 positive regulation of cell migration IEA
 biological_processGO:0031022 nuclear migration along microfilament IEA
 biological_processGO:0034504 protein localization to nucleus IEA
 biological_processGO:0051642 centrosome localization IEA
 biological_processGO:0090286 cytoskeletal anchoring at nuclear membrane IEA
 biological_processGO:1902017 regulation of cilium assembly IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005635 nuclear envelope IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005925 focal adhesion IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016235 aggresome IEA
 cellular_componentGO:0016529 sarcoplasmic reticulum IEA
 cellular_componentGO:0030016 myofibril IEA
 cellular_componentGO:0030018 Z disc IEA
 cellular_componentGO:0031258 lamellipodium membrane IEA
 cellular_componentGO:0031527 filopodium membrane IEA
 cellular_componentGO:0031965 nuclear membrane IEA
 cellular_componentGO:0031981 nuclear lumen IEA
 cellular_componentGO:0034993 meiotic nuclear membrane microtubule tethering complex IEA
 cellular_componentGO:0045111 intermediate filament cytoskeleton IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0051015 actin filament binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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