ENSGALG00000012237


Gallus gallus

Features
Gene ID: ENSGALG00000012237
  
Biological name :POLE2
  
Synonyms : DNA polymerase epsilon subunit 2 / POLE2 / Q5ZKQ6
  
Possible biological names infered from orthology : AC099934.2 / DNA polymerase epsilon 2, accessory subunit / O54956 / P56282 / polymerase (DNA directed), epsilon 2 (p59 subunit)
  
Species: Gallus gallus
  
Chr. number: 5
Strand: -1
Band:
Gene start: 57744141
Gene end: 57763640
  
Corresponding Affymetrix probe sets: GgaAffx.12131.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000050255
Ensembl peptide - ENSGALP00000061368
Ensembl peptide - ENSGALP00000052295
Ensembl peptide - ENSGALP00000019955
NCBI entrez gene - 423567     See in Manteia.
RefSeq - XM_015276729
RefSeq - NM_001006493
RefSeq - XM_015276725
RefSeq - XM_015276726
RefSeq - XM_015276727
RefSeq - XM_015276728
RefSeq Peptide - NP_001006493
swissprot - A0A1L1RRE6
swissprot - A0A1D5PHL5
swissprot - A0A1D5PBX3
swissprot - Q5ZKQ6
Ensembl - ENSGALG00000012237
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pole2ENSDARG00000100028Danio rerio
 POLE2ENSG00000100479Homo sapiens
 AC099934.2ENSMUSG00000113786Mus musculus
 Pole2ENSMUSG00000020974Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR007185  DNA polymerase alpha/epsilon, subunit B
 IPR016266  DNA polymerase epsilon, subunit B
 IPR024639  DNA polymerase epsilon subunit B, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006260 DNA replication IEA
 biological_processGO:0006261 DNA-dependent DNA replication IBA
 biological_processGO:0042276 error-prone translesion synthesis IBA
 biological_processGO:0071897 DNA biosynthetic process IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0008622 epsilon DNA polymerase complex IBA
 cellular_componentGO:0016604 nuclear body IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003887 DNA-directed DNA polymerase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016779 nucleotidyltransferase activity IEA


Pathways (from Reactome)
Pathway description
Recognition of DNA damage by PCNA-containing replication complex
Telomere C-strand synthesis initiation
Nucleotide Excision Repair
PCNA-Dependent Long Patch Base Excision Repair
Termination of translesion DNA synthesis
HDR through Homologous Recombination (HRR)
Dual Incision in GG-NER
Dual incision in TC-NER
DNA replication initiation
Activation of the pre-replicative complex


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000016312 POLA1 / DNA polymerase alpha 1, catalytic subunit / P09884* / P33609* / polymerase (DNA directed), alpha 1*  / complex / reaction
 ENSGALG00000016278 PRIM2 / DNA primase subunit 2 / P33610* / P49643* / DNA primase large subunit *  / complex / reaction
 ENSGALG00000008873 POLE3 / DNA polymerase epsilon 3, accessory subunit / Q9NRF9* / polymerase (DNA directed), epsilon 3 (p17 subunit)*  / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr