ENSGALG00000013143


Gallus gallus

Features
Gene ID: ENSGALG00000013143
  
Biological name :PDE3A
  
Synonyms : PDE3A / phosphodiesterase 3A
  
Possible biological names infered from orthology : phosphodiesterase 3A, cGMP inhibited / Q14432 / Q9Z0X4
  
Species: Gallus gallus
  
Chr. number: 1
Strand: 1
Band:
Gene start: 64936305
Gene end: 65172126
  
Corresponding Affymetrix probe sets: Gga.14256.1.S1_s_at (Chicken Array)   GgaAffx.24123.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000036646
NCBI entrez gene - 418185     See in Manteia.
RefSeq - XM_015291846
RefSeq - XM_015291850
swissprot - E1C0B2
Ensembl - ENSGALG00000013143
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pde3aENSDARG00000004227Danio rerio
 PDE3AENSG00000172572Homo sapiens
 Pde3aENSMUSG00000041741Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PDE3B / cGMP-inhibited 3,5-cyclic phosphodiesterase B / Q13370* / phosphodiesterase 3B*ENSGALG0000000603549
PDE6C / cone cGMP-specific 3,5-cyclic phosphodiesterase subunit alpha / P51160* / Q91ZQ1* / phosphodiesterase 6C*ENSGALG0000000662617
PDE6B / Gallus gallus phosphodiesterase 6B (PDE6B), mRNA. / P35913* / P23440* / phosphodiesterase 6B* / phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide*ENSGALG0000001537317
P0C1Q2* / PDE11A* / Q9HCR9* / phosphodiesterase 11A* / Dual 3,5-cyclic-AMP and -GMP phosphodiesterase 11A *ENSGALG0000004237414
PDE10A / phosphodiesterase 10A / Q8CA95* / Q9Y233*ENSGALG0000001153712
PDE5A / Gallus gallus phosphodiesterase 5A (PDE5A), mRNA. / O76074* / Q8CG03* / phosphodiesterase 5A* / cGMP-specific 3,5-cyclic phosphodiesterase *ENSGALG0000001198212
PDE9A / phosphodiesterase 9A / O70628* / O76083* / High affinity cGMP-specific 3,5-cyclic phosphodiesterase 9A *ENSGALG0000001618611


Protein motifs (from Interpro)
Interpro ID Name
 IPR002073  3"5"-cyclic nucleotide phosphodiesterase, catalytic domain
 IPR003607  HD/PDEase domain
 IPR023174  3"5"-cyclic nucleotide phosphodiesterase, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001556 oocyte maturation IEA
 biological_processGO:0006198 cAMP catabolic process IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0019933 cAMP-mediated signaling IEA
 biological_processGO:0019934 cGMP-mediated signaling IEA
 biological_processGO:0040020 regulation of meiotic nuclear division IEA
 biological_processGO:0042493 response to drug IEA
 biological_processGO:0043116 negative regulation of vascular permeability IEA
 biological_processGO:0043117 positive regulation of vascular permeability IEA
 biological_processGO:0060282 positive regulation of oocyte development IEA
 biological_processGO:0071321 cellular response to cGMP IEA
 biological_processGO:0071560 cellular response to transforming growth factor beta stimulus IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0004114 3",5"-cyclic-nucleotide phosphodiesterase activity IEA
 molecular_functionGO:0004115 3",5"-cyclic-AMP phosphodiesterase activity IEA
 molecular_functionGO:0008081 phosphoric diester hydrolase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
cGMP effects
G alpha (s) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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