ENSGALG00000014250


Gallus gallus

Features
Gene ID: ENSGALG00000014250
  
Biological name :PHOX2B
  
Synonyms : paired like homeobox 2b / PHOX2B
  
Possible biological names infered from orthology : O35690 / Paired mesoderm homeobox protein 2B / Q99453
  
Species: Gallus gallus
  
Chr. number: 4
Strand: 1
Band:
Gene start: 68863939
Gene end: 68865808
  
Corresponding Affymetrix probe sets: Gga.10503.1.S1_at (Chicken Array)   Gga.294.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000036658
NCBI entrez gene - 395548     See in Manteia.
RefSeq - XM_015285470
swissprot - F1NMR6
Ensembl - ENSGALG00000014250
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 phox2bbENSDARG00000091029Danio rerio
 PHOX2BENSG00000109132Homo sapiens
 O35690ENSMUSG00000012520Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ALX4 / ALX homeobox 4 / O35137* / Q9H161* / Homeobox protein aristaless-like 4 *ENSGALG0000003258427
ARX / aristaless related homeobox / O35085* / Q96QS3* / Homeobox protein ARX *ENSGALG0000004260427
ALX1 / ALX homeobox 1 / Q15699* / Q8C8B0* / ALX homeobox protein 1 *ENSGALG0000002721324
DRGX / dorsal root ganglia homeobox / A6NNA5* / Prrxl1* / Q8BYH0* / paired related homeobox protein-like 1*ENSGALG0000003082224
RAX2 / Q9PVY0 / Retinal homeobox protein Rx1 / Q96IS3* / retina and anterior neural fold homeobox 2*ENSGALG0000001343121
ISX / intestine specific homeobox / A1A546* / Q2M1V0*ENSGALG0000001255720
VSX2 / visual system homeobox 2 / P58304* / Q61412*ENSGALG0000003351720
UNCX / UNC homeobox / A6NJT0* / O08934*ENSGALG0000003929220
ENSGALG0000004658420
VSX1 / visual system homeobox 1 / Q91V10* / Q9NZR4*ENSGALG0000003757619
ALX3 / ALX homeobox 3 / O70137* / O95076* / Homeobox protein aristaless-like 3 *ENSGALG0000002586717
RAX / retina and anterior neural fold homeobox / O35602* / Q9Y2V3* / Retinal homeobox protein Rx *ENSGALG0000003327914


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001764 neuron migration IEA
 biological_processGO:0002087 regulation of respiratory gaseous exchange by neurological system process IEA
 biological_processGO:0003357 noradrenergic neuron differentiation IEA
 biological_processGO:0003358 noradrenergic neuron development IEA
 biological_processGO:0003360 brainstem development IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0010001 glial cell differentiation IEA
 biological_processGO:0010468 regulation of gene expression IEA
 biological_processGO:0021533 cell differentiation in hindbrain IEA
 biological_processGO:0021723 medullary reticular formation development IEA
 biological_processGO:0021934 hindbrain tangential cell migration IEA
 biological_processGO:0030182 neuron differentiation IEA
 biological_processGO:0035914 skeletal muscle cell differentiation IEA
 biological_processGO:0045665 negative regulation of neuron differentiation IEA
 biological_processGO:0045666 positive regulation of neuron differentiation IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0048468 cell development IEA
 biological_processGO:0048483 autonomic nervous system development IEA
 biological_processGO:0048484 enteric nervous system development IEA
 biological_processGO:0048485 sympathetic nervous system development IEA
 biological_processGO:0048486 parasympathetic nervous system development IEA
 biological_processGO:0048839 inner ear development IEA
 biological_processGO:0048894 efferent axon development in a lateral line nerve IEA
 biological_processGO:0060541 respiratory system development IEA
 biological_processGO:0061452 retrotrapezoid nucleus neuron differentiation IEA
 biological_processGO:0061549 sympathetic ganglion development IEA
 biological_processGO:0071542 dopaminergic neuron differentiation IEA
 biological_processGO:0071773 cellular response to BMP stimulus IEA
 biological_processGO:1901166 neural crest cell migration involved in autonomic nervous system development IEA
 cellular_componentGO:0000790 nuclear chromatin IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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