ENSGALG00000015184


Gallus gallus

Features
Gene ID: ENSGALG00000015184
  
Biological name :TLE4Z1
  
Synonyms : TLE4Z1 / transducin like enhancer of split 4-Z 1
  
Possible biological names infered from orthology : Q04727 / Q62441 / TLE4 / transducin like enhancer of split 4 / Transducin-like enhancer protein 4
  
Species: Gallus gallus
  
Chr. number: Z
Strand: 1
Band:
Gene start: 38471524
Gene end: 38568782
  
Corresponding Affymetrix probe sets: Gga.10808.1.S1_at (Chicken Array)   Gga.126.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000032172
NCBI entrez gene - 374080     See in Manteia.
RefSeq - NM_204237
RefSeq - XM_015280232
RefSeq Peptide - NP_989568
swissprot - F1N9Y3
Ensembl - ENSGALG00000015184
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 TLE4ENSG00000106829Homo sapiens
 Tle4ENSMUSG00000024642Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TLE1 / transducin like enhancer of split 1 / Q04724* / Q62440* / Transducin-like enhancer protein 1 *ENSGALG0000001257586
TLE3 / transducin like enhancer of split 3 / Q04726* / Q08122*ENSGALG0000000812072
ENSGALG0000003397140
ENSGALG0000004227527
ENSGALG0000003272414
AES / amino-terminal enhancer of split / P63002* / Q08117*ENSGALG0000002950313


Protein motifs (from Interpro)
Interpro ID Name
 IPR001680  WD40 repeat
 IPR005617  Groucho/TLE, N-terminal Q-rich domain
 IPR009146  Groucho/transducin-like enhancer
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017986  WD40-repeat-containing domain
 IPR019775  WD40 repeat, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001709 cell fate determination IMP
 biological_processGO:0003002 regionalization IMP
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007164 establishment of tissue polarity IMP
 biological_processGO:0010628 positive regulation of gene expression IMP
 biological_processGO:0010629 negative regulation of gene expression IMP
 biological_processGO:0030901 midbrain development IMP
 biological_processGO:0048859 formation of anatomical boundary IMP
 cellular_componentGO:0005634 nucleus IEA


Pathways (from Reactome)
Pathway description
Formation of the beta-catenin:TCF transactivating complex
Deactivation of the beta-catenin transactivating complex
Repression of WNT target genes


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000003297 HDAC1 / P56517 / Histone deacetylase 1 / O09106* / Q13547* / Gm10093*  / complex
 ENSGALG00000008883 TCF7L2 / transcription factor 7 like 2 / Q924A0* / Q9NQB0* / transcription factor 7 like 2, T cell specific, HMG box*  / complex / reaction
 ENSGALG00000008491 XIAP / BIRC8* / P98170* / Q60989* / Q96P09* / X-linked inhibitor of apoptosis* / baculoviral IAP repeat containing 8*  / complex / reaction
 ENSGALG00000015184 TLE4Z1 / transducin like enhancer of split 4-Z 1 / TLE4* / Q62441* / Q04727* / transducin like enhancer of split 4* / Transducin-like enhancer protein 4 *  / complex / reaction
 ENSGALG00000012575 TLE1 / transducin like enhancer of split 1 / Q04724* / Q62440* / Transducin-like enhancer protein 1 *  / reaction
 ENSGALG00000037716 UBA52 / ubiquitin A-52 residue ribosomal protein fusion product 1 / P62984* / P62987* / Gm5239* / Gm11808* / predicted gene 11808*  / reaction
 ENSGALG00000036790 P79781 / RPS27A / Ubiquitin-40S ribosomal protein S27a Ubiquitin 40S ribosomal protein S27a / P62983* / P62979* / AL136454.1* / ribosomal protein S27a*  / reaction
 ENSGALG00000031960 LEF1 / lymphoid enhancer binding factor 1 / P27782* / Q9UJU2*  / complex / reaction






 

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