ENSGALG00000015728


Gallus gallus

Features
Gene ID: ENSGALG00000015728
  
Biological name :MUSK
  
Synonyms : muscle, skeletal receptor tyrosine protein kinase precursor / MUSK
  
Possible biological names infered from orthology : muscle associated receptor tyrosine kinase / Muscle, skeletal receptor tyrosine-protein kinase / O15146 / Q61006
  
Species: Gallus gallus
  
Chr. number: Z
Strand: 1
Band:
Gene start: 66717395
Gene end: 66761771
  
Corresponding Affymetrix probe sets: Gga.123.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000025318
Ensembl peptide - ENSGALP00000057598
Ensembl peptide - ENSGALP00000044942
NCBI entrez gene - 373897     See in Manteia.
RefSeq - NM_204108
RefSeq Peptide - NP_989439
swissprot - A0A1D5PXA4
swissprot - A0A1D5NX49
swissprot - F1NDZ8
Ensembl - ENSGALG00000015728
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 muskENSDARG00000098764Danio rerio
 MUSKENSG00000030304Homo sapiens
 MuskENSMUSG00000057280Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NTRK2 / Q91987 / BDNF/NT-3 growth factors receptor / P15209* / Q16620* / neurotrophic receptor tyrosine kinase 2*ENSGALG0000001259423
NTRK3 / Q91044 / NT-3 growth factor receptor / Q16288* / Q6VNS1* / neurotrophic receptor tyrosine kinase 3*ENSGALG0000004024123
ROR1 / receptor tyrosine kinase like orphan receptor 1 / Q01973* / Q9Z139* / Inactive tyrosine-protein kinase transmembrane receptor ROR1 *ENSGALG0000001101922
ROR2 / receptor tyrosine kinase like orphan receptor 2 / Q01974* / Q9Z138*ENSGALG0000001520821
INSR / insulin receptor / P06213* / P15208* / Insulin receptor Insulin receptor subunit alpha Insulin receptor subunit beta*ENSGALG0000004075821
INSRR / insulin receptor related receptor / P14616* / Q9WTL4* / Insulin receptor-related protein Insulin receptor-related protein alpha chain Insulin receptor-related protein beta chain*ENSGALG0000001325320
ROS1 / ROS proto-oncogene 1, receptor tyrosine kinase / P08922* / Q78DX7* / Proto-onco tyrosine-protein kinase ROS *ENSGALG0000001491320
NTRK1 / high affinity nerve growth factor receptor precursor / P04629* / Q3UFB7* / neurotrophic receptor tyrosine kinase 1* / High affinity nerve growth factor receptor *ENSGALG0000001901920
IGF1R / insulin-like growth factor 1 receptor precursor / P08069* / insulin like growth factor 1 receptor*ENSGALG0000004065120
DDR1 / Q03146* / Q08345* / discoidin domain receptor tyrosine kinase 1* / Epithelial discoidin domain-containing receptor 1 *ENSGALG0000000861618
DDR2 / discoidin domain receptor tyrosine kinase 2 / Q16832* / Q62371* / Discoidin domain-containing receptor 2 *ENSGALG0000003932218
PTK7 / inactive tyrosine-protein kinase 7 precursor / Q8BKG3* / Q13308* / Inactive tyrosine-protein kinase 7 * / protein tyrosine kinase 7 (inactive)*ENSGALG0000000860916
LTK / leukocyte receptor tyrosine kinase / P08923* / P29376* / Leukocyte tyrosine kinase receptor *ENSGALG0000000861515
ALK* / P97793* / Q9UM73* / ALK receptor tyrosine kinase* / ALK tyrosine kinase receptor *ENSGALG0000000903411


Protein motifs (from Interpro)
Interpro ID Name
 IPR000001  Kringle
 IPR000719  Protein kinase domain
 IPR001245  Serine-threonine/tyrosine-protein kinase, catalytic domain
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR008266  Tyrosine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR013098  Immunoglobulin I-set
 IPR013783  Immunoglobulin-like fold
 IPR013806  Kringle-like fold
 IPR017441  Protein kinase, ATP binding site
 IPR018056  Kringle, conserved site
 IPR020067  Frizzled domain
 IPR020635  Tyrosine-protein kinase, catalytic domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001934 positive regulation of protein phosphorylation IEA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007528 neuromuscular junction development IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043235 receptor complex IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004713 protein tyrosine kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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