ENSGALG00000024449


Gallus gallus

Features
Gene ID: ENSGALG00000024449
  
Biological name :RAMP2
  
Synonyms : RAMP2 / receptor activity modifying protein 2
  
Possible biological names infered from orthology : O60895 / Q9WUP0
  
Species: Gallus gallus
  
Chr. number: 27
Strand: 1
Band:
Gene start: 5453198
Gene end: 5454993
  
Corresponding Affymetrix probe sets: Gga.12104.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000059229
Ensembl peptide - ENSGALP00000040567
NCBI entrez gene - 420022     See in Manteia.
RefSeq - XM_015299597
RefSeq - NM_001105610
RefSeq - XM_015299596
RefSeq Peptide - NP_001099080
swissprot - A7UH64
Ensembl - ENSGALG00000024449
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ramp2ENSDARG00000037895Danio rerio
 RAMP2ENSG00000131477Homo sapiens
 Ramp2ENSMUSG00000001240Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RAMP1 / receptor activity modifying protein 1 / O60894* / Q9WTJ5* / receptor (calcitonin) activity modifying protein 1*ENSGALG0000000382121
RAMP3 / receptor activity modifying protein 3 / O60896* / Q9WUP1*ENSGALG0000003724621


Protein motifs (from Interpro)
Interpro ID Name
 IPR006985  Receptor activity modifying protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis IEA
 biological_processGO:0001570 vasculogenesis IEA
 biological_processGO:0002040 sprouting angiogenesis IEA
 biological_processGO:0006816 calcium ion transport IEA
 biological_processGO:0006886 intracellular protein transport IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007507 heart development IEA
 biological_processGO:0008217 regulation of blood pressure IEA
 biological_processGO:0008277 regulation of G-protein coupled receptor protein signaling pathway IEA
 biological_processGO:0010628 positive regulation of gene expression IEA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0030816 obsolete positive regulation of cAMP metabolic process IEA
 biological_processGO:0031623 receptor internalization IEA
 biological_processGO:0034333 adherens junction assembly IEA
 biological_processGO:0035924 cellular response to vascular endothelial growth factor stimulus IEA
 biological_processGO:0043116 negative regulation of vascular permeability IEA
 biological_processGO:0045766 positive regulation of angiogenesis IEA
 biological_processGO:0070830 bicellular tight junction assembly IEA
 biological_processGO:0070831 basement membrane assembly IEA
 biological_processGO:0072659 protein localization to plasma membrane IEA
 biological_processGO:0097084 vascular smooth muscle cell development IEA
 biological_processGO:0097647 amylin receptor signaling pathway IEA
 biological_processGO:1990410 adrenomedullin receptor signaling pathway IEA
 biological_processGO:2000352 negative regulation of endothelial cell apoptotic process IEA
 biological_processGO:2001214 positive regulation of vasculogenesis IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043235 receptor complex IEA
 cellular_componentGO:1903143 adrenomedullin receptor complex IEA
 cellular_componentGO:1903440 amylin receptor complex IEA
 molecular_functionGO:0001605 adrenomedullin receptor activity IEA
 molecular_functionGO:0008565 protein transporter activity IEA
 molecular_functionGO:0015026 coreceptor activity IEA
 molecular_functionGO:0097643 amylin receptor activity IEA
 molecular_functionGO:1990409 adrenomedullin binding IEA


Pathways (from Reactome)
Pathway description
G alpha (s) signalling events
Calcitonin-like ligand receptors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000002632 CALCRL / calcitonin receptor like receptor / Q16602* / Q9R1W5* / Calcitonin-related peptide type 1 receptor *  / complex
 ENSGALG00000046593 ADM / adrenomedullin / P35318* / P97297* / ADM Adrenomedullin Proadrenomedullin N-20 terminal peptide*  / complex / reaction






 

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