ENSGALG00000046593


Gallus gallus

Features
Gene ID: ENSGALG00000046593
  
Biological name :ADM
  
Synonyms : ADM / adrenomedullin
  
Possible biological names infered from orthology : ADM Adrenomedullin Proadrenomedullin N-20 terminal peptide / P35318 / P97297
  
Species: Gallus gallus
  
Chr. number: 5
Strand: -1
Band:
Gene start: 8982540
Gene end: 8983767
  
Corresponding Affymetrix probe sets: Gga.12006.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000058799
NCBI entrez gene - 423042     See in Manteia.
RefSeq - XM_015286460
swissprot - A0A1L1RJ79
Ensembl - ENSGALG00000046593
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 admaENSDARG00000015263Danio rerio
 ADMENSG00000148926Homo sapiens
 AdmENSMUSG00000030790Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001710  Adrenomedullin
 IPR021116  Calcitonin/adrenomedullin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001570 vasculogenesis IEA
 biological_processGO:0001843 neural tube closure IEA
 biological_processGO:0002031 G-protein coupled receptor internalization IEA
 biological_processGO:0003073 regulation of systemic arterial blood pressure IEA
 biological_processGO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007507 heart development IEA
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0010460 positive regulation of heart rate IEA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0030816 obsolete positive regulation of cAMP metabolic process IEA
 biological_processGO:0031623 receptor internalization IEA
 biological_processGO:0035809 regulation of urine volume IEA
 biological_processGO:0043116 negative regulation of vascular permeability IEA
 biological_processGO:0045766 positive regulation of angiogenesis IEA
 biological_processGO:0045906 negative regulation of vasoconstriction IEA
 biological_processGO:0048589 developmental growth IEA
 biological_processGO:0060670 branching involved in labyrinthine layer morphogenesis IEA
 biological_processGO:0060712 spongiotrophoblast layer development IEA
 biological_processGO:0097084 vascular smooth muscle cell development IEA
 biological_processGO:0097647 amylin receptor signaling pathway IEA
 biological_processGO:1990410 adrenomedullin receptor signaling pathway IEA
 biological_processGO:2001214 positive regulation of vasculogenesis IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0005179 hormone activity IEA
 molecular_functionGO:0031700 adrenomedullin receptor binding IEA


Pathways (from Reactome)
Pathway description
G alpha (s) signalling events
Calcitonin-like ligand receptors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000002632 CALCRL / calcitonin receptor like receptor / Q16602* / Q9R1W5* / Calcitonin-related peptide type 1 receptor *  / complex / reaction
 ENSGALG00000024449 RAMP2 / receptor activity modifying protein 2 / O60895* / Q9WUP0*  / complex / reaction
 ENSGALG00000037246 RAMP3 / receptor activity modifying protein 3 / O60896* / Q9WUP1*  / complex / reaction






 

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