ENSGALG00000002632


Gallus gallus

Features
Gene ID: ENSGALG00000002632
  
Biological name :CALCRL
  
Synonyms : calcitonin receptor like receptor / CALCRL
  
Possible biological names infered from orthology : Calcitonin-related peptide type 1 receptor / Q16602 / Q9R1W5
  
Species: Gallus gallus
  
Chr. number: 7
Strand: 1
Band:
Gene start: 1088699
Gene end: 1148350
  
Corresponding Affymetrix probe sets: Gga.10326.1.S1_s_at (Chicken Array)   GgaAffx.25557.1.S1_at (Chicken Array)   GgaAffx.25557.2.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000004138
NCBI entrez gene - 423990     See in Manteia.
RefSeq - NM_001163650
RefSeq Peptide - NP_001157122
swissprot - C5HV42
Ensembl - ENSGALG00000002632
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 calcrlaENSDARG00000011473Danio rerio
 calcrlbENSDARG00000011571Danio rerio
 CALCRLENSG00000064989Homo sapiens
 CalcrlENSMUSG00000059588Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ENSGALG0000000950961
CRHR1 / corticotropin-releasing factor receptor 1 precursor / P35347* / P34998* / LINC02210-CRHR1* / LINC02210-CRHR1 readthrough* / Corticotropin-releasing factor receptor 1 * / corticotro...ENSGALG0000000037126
CRHR2 / corticotropin-releasing factor receptor 2 / Q13324* / Q60748* / corticotropin releasing hormone receptor 2*ENSGALG0000000565725


Protein motifs (from Interpro)
Interpro ID Name
 IPR000832  GPCR, family 2, secretin-like
 IPR001879  GPCR, family 2, extracellular hormone receptor domain
 IPR003287  GPCR, family 2, calcitonin receptor family
 IPR003289  GPCR, family 2, calcitonin gene-related peptide, type 1 receptor
 IPR017981  GPCR, family 2-like
 IPR017983  GPCR, family 2, secretin-like, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis IEA
 biological_processGO:0006816 calcium ion transport IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007166 cell surface receptor signaling pathway IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007507 heart development IEA
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0031623 receptor internalization IEA
 biological_processGO:0048661 positive regulation of smooth muscle cell proliferation IEA
 biological_processGO:0071329 cellular response to sucrose stimulus IEA
 biological_processGO:1990408 calcitonin gene-related peptide receptor signaling pathway IEA
 biological_processGO:1990410 adrenomedullin receptor signaling pathway IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005764 lysosome IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:1903143 adrenomedullin receptor complex IEA
 cellular_componentGO:1990406 CGRP receptor complex IEA
 molecular_functionGO:0001605 adrenomedullin receptor activity IEA
 molecular_functionGO:0001635 calcitonin gene-related peptide receptor activity IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0004948 calcitonin receptor activity IEA
 molecular_functionGO:0008565 protein transporter activity IEA
 molecular_functionGO:1990409 adrenomedullin binding IEA


Pathways (from Reactome)
Pathway description
G alpha (s) signalling events
Calcitonin-like ligand receptors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000024449 RAMP2 / receptor activity modifying protein 2 / O60895* / Q9WUP0*  / complex
 ENSGALG00000046593 ADM / adrenomedullin / P35318* / P97297* / ADM Adrenomedullin Proadrenomedullin N-20 terminal peptide*  / complex / reaction
 ENSGALG00000003821 RAMP1 / receptor activity modifying protein 1 / O60894* / Q9WTJ5* / receptor (calcitonin) activity modifying protein 1*  / complex
 ENSGALG00000006054 CALCB / calcitonin gene-related peptide isoform 3 preproprotein / CALCA* / P01258* / P06881* / P70160* / Q99JA0* / Calcitonin-related peptide 1 * / calcitonin related polypeptide alpha*  / complex / reaction
 ENSGALG00000037246 RAMP3 / receptor activity modifying protein 3 / O60896* / Q9WUP1*  / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr