ENSGALG00000027786


Gallus gallus

Features
Gene ID: ENSGALG00000027786
  
Biological name :SOCS3
  
Synonyms : SOCS3 / suppressor of cytokine signaling 3
  
Possible biological names infered from orthology : O14543 / O35718
  
Species: Gallus gallus
  
Chr. number: 18
Strand: 1
Band:
Gene start: 9931036
Gene end: 9933083
  
Corresponding Affymetrix probe sets: Gga.915.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000042295
NCBI entrez gene - 395299     See in Manteia.
RefSeq - NM_204600
RefSeq Peptide - NP_989931
swissprot - R4GJH9
Ensembl - ENSGALG00000027786
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 socs3aENSDARG00000025428Danio rerio
 socs3bENSDARG00000026611Danio rerio
 SOCS3ENSG00000184557Homo sapiens
 Socs3ENSMUSG00000053113Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CISH / cytokine-inducible SH2-containing protein / Q62225* / Q9NSE2*ENSGALG0000000226031
SOCS1 / suppressor of cytokine signaling 1 / O15524* / O35716*ENSGALG0000000715830
SOCS2 / suppressor of cytokine signaling 2 / O14508* / O35717*ENSGALG0000001129525
SOCS6 / suppressor of cytokine signaling 6 / O14544* / Q9JLY0*ENSGALG0000001373125
SOCS1L / uncharacterized protein LOC417978 ENSGALG0000002319324
SOCS7* / O14512* / Q8VHQ2* / suppressor of cytokine signaling 7*ENSGALG0000004065823
SOCS5 / suppressor of cytokine signaling 5 / O54928* / O75159*ENSGALG0000001001622
SOCS4 / suppressor of cytokine signaling 4 / Q8WXH5* / Q91ZA6*ENSGALG0000001217922


Protein motifs (from Interpro)
Interpro ID Name
 IPR000980  SH2 domain
 IPR001496  SOCS box domain
 IPR028414  Suppressor of cytokine signalling 3


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001932 regulation of protein phosphorylation IEA
 biological_processGO:0007259 JAK-STAT cascade IEA
 biological_processGO:0009968 negative regulation of signal transduction IEA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0042532 negative regulation of tyrosine phosphorylation of STAT protein IEA
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 biological_processGO:0045595 regulation of cell differentiation IEA
 biological_processGO:0045597 positive regulation of cell differentiation IEA
 biological_processGO:0046426 negative regulation of JAK-STAT cascade IEA
 biological_processGO:0046627 negative regulation of insulin receptor signaling pathway IEA
 biological_processGO:0050728 negative regulation of inflammatory response IEA
 biological_processGO:0060670 branching involved in labyrinthine layer morphogenesis IEA
 biological_processGO:0060674 placenta blood vessel development IEA
 biological_processGO:0060707 trophoblast giant cell differentiation IEA
 biological_processGO:0060708 spongiotrophoblast differentiation IEA
 biological_processGO:1990830 cellular response to leukemia inhibitory factor IEA
 cellular_componentGO:0005622 intracellular IEA
 molecular_functionGO:0001784 phosphotyrosine residue binding IEA


Pathways (from Reactome)
Pathway description
Interleukin-6 signaling
Interferon gamma signaling
Regulation of IFNG signaling
Interferon alpha/beta signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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