ENSGALG00000029381


Gallus gallus

Features
Gene ID: ENSGALG00000029381
  
Biological name :TAP2
  
Synonyms : TAP2
  
Possible biological names infered from orthology : AL669918.1 / P36371 / Q03519 / transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) / transporter 2, ATP binding cassette subfamily B member
  
Species: Gallus gallus
  
Chr. number: 16
Strand: -1
Band:
Gene start: 78333
Gene end: 81467
  
Corresponding Affymetrix probe sets: Gga.2865.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000044374
NCBI entrez gene - 427728     See in Manteia.
RefSeq - NM_001099357
RefSeq - XM_015294990
RefSeq - XM_015294991
RefSeq Peptide - NP_001092827
swissprot - A5HUM1
Ensembl - ENSGALG00000029381
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tap2aENSDARG00000036787Danio rerio
 tap2tENSDARG00000033446Danio rerio
 AL669918.1ENSG00000250264Homo sapiens
 TAP2ENSG00000204267Homo sapiens
 Tap2ENSMUSG00000024339Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ABCB9 / ATP binding cassette subfamily B member 9 / Q9JJ59* / Q9NP78* / ATP-binding cassette, sub-family B (MDR/TAP), member 9*ENSGALG0000000373636
TAP1 / antigen peptide transporter 1 / Q03518* / P21958* / transporter 1, ATP binding cassette subfamily B member* / transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)*ENSGALG0000003507530
ABCB10 / ATP binding cassette subfamily B member 10 / Q9JI39* / Q9NRK6* / ATP-binding cassette, sub-family B (MDR/TAP), member 10*ENSGALG0000001109626


Protein motifs (from Interpro)
Interpro ID Name
 IPR003439  ABC transporter-like
 IPR003593  AAA+ ATPase domain
 IPR005293  Antigen peptide transporter 2
 IPR011527  ABC transporter type 1, transmembrane domain
 IPR017871  ABC transporter, conserved site
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001916 positive regulation of T cell mediated cytotoxicity IEA
 biological_processGO:0002237 response to molecule of bacterial origin IEA
 biological_processGO:0002481 antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent IEA
 biological_processGO:0002485 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent IEA
 biological_processGO:0002489 antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent IEA
 biological_processGO:0015833 peptide transport IEA
 biological_processGO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I IEA
 biological_processGO:0042886 amide transport IEA
 biological_processGO:0055085 transmembrane transport IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030176 integral component of endoplasmic reticulum membrane IEA
 cellular_componentGO:0042825 TAP complex IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0015440 peptide-transporting ATPase activity IEA
 molecular_functionGO:0016887 ATPase activity IEA
 molecular_functionGO:0042287 MHC protein binding IEA
 molecular_functionGO:0042626 ATPase activity, coupled to transmembrane movement of substances IEA
 molecular_functionGO:0046978 TAP1 binding IEA


Pathways (from Reactome)
Pathway description
ER-Phagosome pathway
Antigen Presentation: Folding, assembly and peptide loading of class I MHC


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000008022 TAPBP / TAP binding protein / O15533*  / reaction
 ENSGALG00000039704 Q5ZJW4 / SEC22B / Vesicle-trafficking protein SEC22b / O08547* / O75396* / SEC22 homolog B, vesicle trafficking protein (gene/pseudogene)*  / reaction






 

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