ENSGALG00000029652


Gallus gallus

Features
Gene ID: ENSGALG00000029652
  
Biological name :OPHN1
  
Synonyms : oligophrenin 1 / OPHN1
  
Possible biological names infered from orthology : O60890 / Q99J31
  
Species: Gallus gallus
  
Chr. number: 4
Strand: -1
Band:
Gene start: 503169
Gene end: 547399
  
Corresponding Affymetrix probe sets: Gga.14239.1.S1_at (Chicken Array)   Gga.15715.1.S1_at (Chicken Array)   Gga.16346.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000043860
Ensembl peptide - ENSGALP00000045591
NCBI entrez gene - 422162     See in Manteia.
RefSeq - XM_015278326
RefSeq - XM_015278327
RefSeq - XM_015278328
swissprot - A0A1D5NYY0
swissprot - A0A1D5NU51
Ensembl - ENSGALG00000029652
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ophn1ENSDARG00000035420Danio rerio
 OPHN1ENSG00000079482Homo sapiens
 Ophn1ENSMUSG00000031214Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ARHGAP42 / Rho GTPase activating protein 42 / A6NI28* / B2RQE8* / Q9H2Q1*ENSGALG0000001719650
Q5ZMW5 / ARHGAP26 / Rho GTPase-activating protein 26 / Q6ZQ82* / Q9UNA1*ENSGALG0000003393842
ARHGAP10 / Rho GTPase activating protein 10 / A1A4S6* / Q6Y5D8*ENSGALG0000001003141
ARHGAP29 / Rho GTPase activating protein 29 / Q52LW3* / Q8CGF1* / Mus musculus Rho GTPase activating protein 29 (Arhgap29), transcript variant 2, mRNA.*ENSGALG0000000568317
ARHGAP45 / minor histocompatibility protein HA-1 / Q3TBD2* / Q92619* / Rho GTPase activating protein 45* / Mus musculus Rho GTPase activating protein 45 (Arhgap45), transcript variant 3, mRNA.*ENSGALG0000003246914
ARHGAP31 / Rho GTPase activating protein 31 / A6X8Z5* / Q2M1Z3*ENSGALG0000001507711
ENSGALG0000001125210
RACGAP1 / Rac GTPase activating protein 1 / Q9H0H5* / Q9WVM1*ENSGALG0000003323110
RALBP1 / ralA binding protein 1 / Q15311* / Q62172*ENSGALG000000084058
ARHGAP32 / Rho GTPase activating protein 32 / A7KAX9* / Q811P8*ENSGALG000000435116
ENSGALG000000454605
ENSGALG000000441714
ENSGALG000000442034
ENSGALG000000445354
ENSGALG000000446034
ENSGALG000000447584
ENSGALG000000454054
ENSGALG000000458544
ENSGALG000000458814
ENSGALG000000460314


Protein motifs (from Interpro)
Interpro ID Name
 IPR000198  Rho GTPase-activating protein domain
 IPR001849  Pleckstrin homology domain
 IPR008936  Rho GTPase activation protein
 IPR011993  PH-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0021707 cerebellar granule cell differentiation IEA
 biological_processGO:0021895 cerebral cortex neuron differentiation IEA
 biological_processGO:0030036 actin cytoskeleton organization IEA
 biological_processGO:0030100 regulation of endocytosis IEA
 biological_processGO:0030182 neuron differentiation IEA
 biological_processGO:0031175 neuron projection development IEA
 biological_processGO:0034329 cell junction assembly IEA
 biological_processGO:0035023 regulation of Rho protein signal transduction IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0045198 establishment of epithelial cell apical/basal polarity IEA
 biological_processGO:0048488 synaptic vesicle endocytosis IEA
 biological_processGO:0048667 cell morphogenesis involved in neuron differentiation IEA
 biological_processGO:0051966 regulation of synaptic transmission, glutamatergic IEA
 biological_processGO:1901799 negative regulation of proteasomal protein catabolic process IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0015629 actin cytoskeleton IEA
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0043195 terminal bouton IEA
 cellular_componentGO:0043197 dendritic spine IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005096 GTPase activator activity IEA
 molecular_functionGO:0005543 phospholipid binding IEA


Pathways (from Reactome)
Pathway description
Rho GTPase cycle


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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