ENSGALG00000033231


Gallus gallus

Features
Gene ID: ENSGALG00000033231
  
Biological name :RACGAP1
  
Synonyms : RACGAP1 / Rac GTPase activating protein 1
  
Possible biological names infered from orthology : Q9H0H5 / Q9WVM1
  
Species: Gallus gallus
  
Chr. number: 33
Strand: 1
Band:
Gene start: 341448
Gene end: 349070
  
Corresponding Affymetrix probe sets: Gga.11635.1.S1_at (Chicken Array)   Gga.11776.1.S1_s_at (Chicken Array)   Gga.1533.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000055484
Ensembl peptide - ENSGALP00000061204
NCBI entrez gene - 426884     See in Manteia.
RefSeq - XM_004949732
swissprot - A0A1D5PRF9
swissprot - A0A1L1RQX2
Ensembl - ENSGALG00000033231
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 racgap1ENSDARG00000015460Danio rerio
 Q9H0H5ENSG00000161800Homo sapiens
 Q9WVM1ENSMUSG00000023015Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ENSGALG0000001125235
ARHGAP29 / Rho GTPase activating protein 29 / Q52LW3* / Q8CGF1* / Mus musculus Rho GTPase activating protein 29 (Arhgap29), transcript variant 2, mRNA.*ENSGALG0000000568320
ARHGAP45 / minor histocompatibility protein HA-1 / Q3TBD2* / Q92619* / Rho GTPase activating protein 45* / Mus musculus Rho GTPase activating protein 45 (Arhgap45), transcript variant 3, mRNA.*ENSGALG0000003246918
ARHGAP42 / Rho GTPase activating protein 42 / A6NI28* / B2RQE8* / Q9H2Q1*ENSGALG0000001719613
OPHN1 / oligophrenin 1 / O60890* / Q99J31*ENSGALG0000002965213
ARHGAP10 / Rho GTPase activating protein 10 / A1A4S6* / Q6Y5D8*ENSGALG0000001003112
ARHGAP31 / Rho GTPase activating protein 31 / A6X8Z5* / Q2M1Z3*ENSGALG0000001507712
Q5ZMW5 / ARHGAP26 / Rho GTPase-activating protein 26 / Q6ZQ82* / Q9UNA1*ENSGALG0000003393812
RALBP1 / ralA binding protein 1 / Q15311* / Q62172*ENSGALG0000000840511
ENSGALG000000454606
ARHGAP32 / Rho GTPase activating protein 32 / A7KAX9* / Q811P8*ENSGALG000000435115
ENSGALG000000441715
ENSGALG000000442035
ENSGALG000000445355
ENSGALG000000446035
ENSGALG000000447585
ENSGALG000000454055
ENSGALG000000458545
ENSGALG000000458815
ENSGALG000000460315


Protein motifs (from Interpro)
Interpro ID Name
 IPR000198  Rho GTPase-activating protein domain
 IPR002219  Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
 IPR008936  Rho GTPase activation protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000281 mitotic cytokinesis IEA
 biological_processGO:0000915 actomyosin contractile ring assembly IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007283 spermatogenesis IEA
 biological_processGO:0007405 neuroblast proliferation IEA
 biological_processGO:0008272 sulfate transport IEA
 biological_processGO:0032467 positive regulation of cytokinesis IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0045995 regulation of embryonic development IEA
 biological_processGO:0051256 mitotic spindle midzone assembly IEA
 biological_processGO:0051988 regulation of attachment of spindle microtubules to kinetochore IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0030496 midbody IEA
 cellular_componentGO:0031234 extrinsic component of cytoplasmic side of plasma membrane IEA
 cellular_componentGO:0032154 cleavage furrow IEA
 cellular_componentGO:0051233 spindle midzone IEA
 cellular_componentGO:0072686 mitotic spindle IEA
 cellular_componentGO:0097149 centralspindlin complex IEA
 molecular_functionGO:0005096 GTPase activator activity IEA
 molecular_functionGO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding IEA
 molecular_functionGO:0008017 microtubule binding IEA
 molecular_functionGO:0019901 protein kinase binding IEA
 molecular_functionGO:0043014 alpha-tubulin binding IEA
 molecular_functionGO:0043015 gamma-tubulin binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0048487 beta-tubulin binding IEA


Pathways (from Reactome)
Pathway description
Rho GTPase cycle
COPI-dependent Golgi-to-ER retrograde traffic
Kinesins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000033231 RACGAP1 / Rac GTPase activating protein 1 / Q9H0H5* / Q9WVM1*  / complex / reaction






 

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