ENSGALG00000033511


Gallus gallus

Features
Gene ID: ENSGALG00000033511
  
Biological name :CYP8B1
  
Synonyms : CYP8B1 / cytochrome P450, family 8, subfamily B
  
Possible biological names infered from orthology : cytochrome P450 family 8 subfamily B member 1 / Q9UNU6
  
Species: Gallus gallus
  
Chr. number: 2
Strand: 1
Band:
Gene start: 2104464
Gene end: 2106136
  
Corresponding Affymetrix probe sets: Gga.10231.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000044418
NCBI entrez gene - 425055     See in Manteia.
RefSeq - NM_001005571
RefSeq Peptide - NP_001005571
swissprot - A0A1D5NVP2
Ensembl - ENSGALG00000033511
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cyp8b1ENSDARG00000053068Danio rerio
 cyp8b2ENSDARG00000097556Danio rerio
 cyp8b3ENSDARG00000097559Danio rerio
 CYP8B1ENSG00000180432Homo sapiens
 Cyp8b1ENSMUSG00000050445Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CYP7A1 / cholesterol 7-alpha-monooxygenase / P22680* / Q64505* / cytochrome P450 family 7 subfamily A member 1*ENSGALG0000004122231
CYP7B1 / cytochrome P450 family 7 subfamily B member 1 / O75881* / Q60991* / 25-hydroxycholesterol 7-alpha-hydroxylase *ENSGALG0000002943530
CYP39A1 / cytochrome P450 family 39 subfamily A member 1 / Q9JKJ9* / Q9NYL5* / 24-hydroxycholesterol 7-alpha-hydroxylase *ENSGALG0000001671019


Protein motifs (from Interpro)
Interpro ID Name
 IPR001128  Cytochrome P450
 IPR002403  Cytochrome P450, E-class, group IV
 IPR024204  Cytochrome P450, cholesterol 7-alpha-monooxygenase-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004497 monooxygenase activity IEA
 molecular_functionGO:0005506 iron ion binding IEA
 molecular_functionGO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
 molecular_functionGO:0020037 heme binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
Synthesis of bile acids and bile salts via 24-hydroxycholesterol
Synthesis of bile acids and bile salts via 27-hydroxycholesterol
Sterols are 12-hydroxylated by CYP8B1


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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