ENSGALG00000038454


Gallus gallus

Features
Gene ID: ENSGALG00000038454
  
Biological name :PDX1
  
Synonyms : pancreatic and duodenal homeobox 1 / PDX1
  
Possible biological names infered from orthology : P52945 / P52946 / Pancreas/duodenum homeobox protein 1
  
Species: Gallus gallus
  
Chr. number: 1
Strand: -1
Band:
Gene start: 176082150
Gene end: 176084982
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSGALP00000054383
NCBI entrez gene - 771348     See in Manteia.
RefSeq - XM_001234635
swissprot - A0A1D5PNE2
Ensembl - ENSGALG00000038454
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pdx1ENSDARG00000002779Danio rerio
 PDX1ENSG00000139515Homo sapiens
 Pdx1ENSMUSG00000029644Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HOXA3 / homeobox A3 / O43365* / P02831* / Homeobox protein Hox-A3 *ENSGALG0000002792531
HOXD3 / homeobox D3 / P09027* / P31249*ENSGALG0000002342030
HOXA2 / Q08727 / Homeobox protein Hox-A2 / O43364* / P31245* / homeobox A2*ENSGALG0000004052130
HOXB3 / P09026* / P14651* / homeobox B3* / Homeobox protein Hox-B3 *ENSGALG0000004321930
HOXB1ENSGALG0000001345427
HOXA1 / homeobox A1 / P49639*ENSGALG0000002809526
GSX1 / GS homeobox 1 / P31315* / Q9H4S2*ENSGALG0000002977926
GSX2* / P31316* / Q9BZM3* / GS homeobox 2*ENSGALG0000003594326
HOXB2 / homeobox B2 / P0C1T1* / P14652* / Homeobox protein Hox-B2 *ENSGALG0000002577421


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site
 IPR020479  Homeobox domain, metazoa


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0001889 liver development IEA
 biological_processGO:0003309 type B pancreatic cell differentiation IEA
 biological_processGO:0006006 glucose metabolic process IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0007263 nitric oxide mediated signal transduction IEA
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0016331 morphogenesis of embryonic epithelium IEA
 biological_processGO:0030073 insulin secretion IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0031016 pancreas development IEA
 biological_processGO:0031017 exocrine pancreas development IEA
 biological_processGO:0031018 endocrine pancreas development IEA
 biological_processGO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus IEA
 biological_processGO:0042127 regulation of cell proliferation IEA
 biological_processGO:0042593 glucose homeostasis IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0048565 digestive tract development IEA
 biological_processGO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway IEA
 biological_processGO:2000675 negative regulation of type B pancreatic cell apoptotic process IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0016607 nuclear speck IEA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003682 chromatin binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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