ENSGALG00000040045


Gallus gallus

Features
Gene ID: ENSGALG00000040045
  
Biological name :DBH
  
Synonyms : DBH / dopamine beta-hydroxylase
  
Possible biological names infered from orthology : Dopamine beta-hydroxylase Soluble dopamine beta-hydroxylase / P09172 / Q64237
  
Species: Gallus gallus
  
Chr. number: 17
Strand: 1
Band:
Gene start: 7488110
Gene end: 7499098
  
Corresponding Affymetrix probe sets: Gga.295.1.S1_at (Chicken Array)   GgaAffx.1867.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000044761
Ensembl peptide - ENSGALP00000047529
NCBI entrez gene - 395549     See in Manteia.
RefSeq - XM_415429
swissprot - A0A1D5NWM1
swissprot - A0A1D5P4C1
Ensembl - ENSGALG00000040045
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dbhENSDARG00000069446Danio rerio
 DBHENSG00000123454Homo sapiens
 DbhENSMUSG00000000889Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MOXD1 / DBH-like monooxygenase protein 1 precursor / Q6UVY6* / Q9CXI3* / monooxygenase DBH like 1* / DBH-like monooxygenase protein 1 *ENSGALG0000000291124
PAM / peptidylglycine alpha-amidating monooxygenase / P19021* / P97467*ENSGALG0000001525615


Protein motifs (from Interpro)
Interpro ID Name
 IPR000323  Copper type II, ascorbate-dependent monooxygenase, N-terminal
 IPR005018  DOMON domain
 IPR008977  PHM/PNGase F domain superfamily
 IPR014784  Copper type II, ascorbate-dependent monooxygenase-like, C-terminal
 IPR020611  Copper type II, ascorbate-dependent monooxygenase, histidine-cluster-1 conserved site
 IPR024548  Copper type II ascorbate-dependent monooxygenase, C-terminal
 IPR028460  Tyramine beta-hydroxylase/Dopamine beta-hydroxylase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001816 cytokine production IEA
 biological_processGO:0001974 blood vessel remodeling IEA
 biological_processGO:0001975 response to amphetamine IEA
 biological_processGO:0002443 leukocyte mediated immunity IEA
 biological_processGO:0007613 memory IEA
 biological_processGO:0007626 locomotory behavior IEA
 biological_processGO:0008306 associative learning IEA
 biological_processGO:0008542 visual learning IEA
 biological_processGO:0042127 regulation of cell proliferation IEA
 biological_processGO:0042309 homoiothermy IEA
 biological_processGO:0042420 dopamine catabolic process IEA
 biological_processGO:0042421 norepinephrine biosynthetic process IEA
 biological_processGO:0042593 glucose homeostasis IEA
 biological_processGO:0042596 fear response IEA
 biological_processGO:0042711 maternal behavior IEA
 biological_processGO:0045907 positive regulation of vasoconstriction IEA
 biological_processGO:0048149 behavioral response to ethanol IEA
 biological_processGO:0048265 response to pain IEA
 biological_processGO:0050900 leukocyte migration IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:2001236 regulation of extrinsic apoptotic signaling pathway IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030667 secretory granule membrane IEA
 cellular_componentGO:0034774 secretory granule lumen IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004497 monooxygenase activity IEA
 molecular_functionGO:0004500 dopamine beta-monooxygenase activity IEA
 molecular_functionGO:0005507 copper ion binding IEA
 molecular_functionGO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen IEA


Pathways (from Reactome)
Pathway description
Catecholamine biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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