ENSGALG00000042356


Gallus gallus
regulationFSTL3signalingpathwayactivinbindingdomaindifferentiationtranscriptionrnapolymeraseiireceptorproteininsulin-likegrowthfactorkazalfollistatin-liken-terminaltbhematopoieticprogenitorcellcell-celladhesionbmposteoclasttransmembraneserinethreonine

Features
Gene ID: ENSGALG00000042356
  
Biological name :FSTL3
  
Synonyms : follistatin like 3 / FSTL3
  
Possible biological names infered from orthology : Follistatin-related protein 3 / O95633 / Q9EQC7
  
Species: Gallus gallus
  
Chr. number: 28
Strand: 1
Band:
Gene start: 2762167
Gene end: 2769464
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSGALP00000045852
NCBI entrez gene - 770427     See in Manteia.
RefSeq - XM_001233760
swissprot - A0A1D5NZN4
Ensembl - ENSGALG00000042356
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fstl3ENSDARG00000025670Danio rerio
 FSTL3ENSG00000070404Homo sapiens
 Fstl3ENSMUSG00000020325Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FST / follistatin precursor / P19883* / follistatin* / follistatin FST315 *ENSGALG0000001490838


Protein motifs (from Interpro)
Interpro ID Name
 IPR002350  Kazal domain
 IPR003645  Follistatin-like, N-terminal
 IPR017878  TB domain


Gene Ontology (GO)
anatomical structure developmentcellular developmental processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell adhesioncell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimulusanatomical structure developmentcellular developmental processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell adhesioncell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimulusanatomical structure developmentcellular developmental processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell adhesioncell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimulusanatomical structure developmentcellular developmental processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell adhesioncell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimulusanatomical structure developmentcellular developmental processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell adhesioncell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimulusanatomical structure developmentcellular developmental processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell adhesioncell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimulusanatomical structure developmentcellular developmental processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell adhesioncell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimulusanatomical structure developmentcellular developmental processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell adhesioncell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimulusanatomical structure developmentcellular developmental processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell adhesioncell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimulusanatomical structure developmentcellular developmental processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell adhesioncell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimulusanatomical anatomical structure developmentcellular decellular developmental processnitrogen conitrogen compound metabolic processbiosynthetibiosynthetic processcellular mecellular metabolic processprimary metprimary metabolic processorganic suborganic substance metabolic processcell adhesicell adhesioncell communcell communicationresponse toresponse to endogenous stimulusresponse toresponse to chemicalcellular recellular response to stimulus
protein bindingprotein-containing complex bindingprotein bindingprotein-containing complex bindingprotein bindingprotein-containing complex bindingprotein bindingprotein-containing complex bindingprotein bindingprotein-containing complex bindingprotein bindingprotein-containing complex bindingprotein bindingprotein-containing complex bindingprotein bindingprotein-containing complex bindingprotein bindingprotein-containing complex bindingprotein bindingprotein-containing complex bindingprotein bindingprotein bindingprotein-containing complex bindingprotein-containing complex binding
extracellular regioncellorganellemembrane-enclosed lumenextracellular regioncellorganellemembrane-enclosed lumenextracellular regioncellorganellemembrane-enclosed lumenextracellular regioncellorganellemembrane-enclosed lumenextracellular regioncellorganellemembrane-enclosed lumenextracellular regioncellorganellemembrane-enclosed lumenextracellular regioncellorganellemembrane-enclosed lumenextracellular regioncellorganellemembrane-enclosed lumenextracellular regioncellorganellemembrane-enclosed lumenextracellular regioncellorganellemembrane-enclosed lumenextracellular regionextracellular regioncellcellorganelleorganellemembrane-enclosed lumenmembrane-enclosed lumen
TypeGO IDTermEv.Code
 biological_processGO:0002244 hematopoietic progenitor cell differentiation IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0022409 positive regulation of cell-cell adhesion IEA
 biological_processGO:0030514 negative regulation of BMP signaling pathway IEA
 biological_processGO:0032926 negative regulation of activin receptor signaling pathway IEA
 biological_processGO:0045671 negative regulation of osteoclast differentiation IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0090101 negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 molecular_functionGO:0001968 fibronectin binding IEA
 molecular_functionGO:0048185 activin binding IEA


Pathways (from Reactome)
Pathway description
Antagonism of Activin by Follistatin
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Post-translational protein phosphorylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000028770 INHBB / inhibin beta B chain precursor / P09529* / Q04999* / Inhibin beta B chain * / inhibin beta B subunit*  / complex / reaction
 ENSGALG00000034616 INHBA / inhibin beta A chain precursor / P08476* / Q04998* / Inhibin beta A chain * / inhibin beta A subunit*  / complex / reaction
 ENSGALG00000042356 FSTL3 / follistatin like 3 / O95633* / Q9EQC7* / Follistatin-related protein 3 *  / complex / reaction






 

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